Anti-GPCR GPR120 抗体 (ab118757)

製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to GPCR GPR120
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 243-292 (VVTHSEITKA SRKRLTVSLA YSESHQIRVS QQDFRLFRTL FLLMVSFFIM) of Human GPCR GPR120.

  • ポジティブ・コントロール
    • HepG2 cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab118757 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 42 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能
    Receptor for medium and long-chain free fatty acid (FAA). Signals via a G(q)/G(11)-coupled pathway. Acts as a receptor for omega-3 fatty acids and mediates robust anti-inflammatory effects particulary in macrophages and fat cells. The anti-inflammatory effects involve inhibition of TAK1 through a beta-arrestin 2 (ARRB2)/TAB1 dependent effect but independent of G(q)/G(11)-coupled pathway. Mediates potent insulin sensitizing and antidiabetic effects by repressing macrophage-induced tissue inflammation. May mediates the taste of fatty acids.
  • 組織特異性
    Abundant expression in the intestinal tract.
  • 配列類似性
    Belongs to the G-protein coupled receptor 1 family.
  • 翻訳後修飾
    Phosphorylated. FFA stimulation facilitates phosphorylation.
  • 細胞内局在
    Cell membrane. Colocalized with ARRB2 following DHA treatment.
  • Information by UniProt
  • 参照データベース
  • 別名
    • BMIQ10 antibody
    • FFAR4 antibody
    • Free fatty acid receptor 4 antibody
    • G protein coupled receptor 120 antibody
    • G protein coupled receptor 129 antibody
    • G protein coupled receptor GT01 antibody
    • G protein coupled receptor PGR 4 antibody
    • G protein coupled receptor PGR4 antibody
    • G-protein coupled receptor 120 antibody
    • G-protein coupled receptor 129 antibody
    • G-protein coupled receptor GT01 antibody
    • G-protein coupled receptor PGR4 antibody
    • GPR 120 antibody
    • GPR 129 antibody
    • GPR120 antibody
    • GPR129 antibody
    • GT01 antibody
    • HGNC:19345 antibody
    • MGC119984 antibody
    • O3FA1_HUMAN antibody
    • O3FAR1 antibody
    • Omega-3 fatty acid receptor 1 antibody
    • PGR 4 antibody
    • PGR4 antibody
    see all

Anti-GPCR GPR120 antibody 画像

  • Anti-GPCR GPR120 antibody (ab118757) at 1 µg/ml + HepG2 cell lysate at 10 µg

    Predicted band size : 42 kDa

プロトコール

Anti-GPCR GPR120 antibody (ab118757) 使用論文

ab118757 has not yet been referenced specifically in any publications.

Product Wall

Application
Western blot
Sample
Rat Tissue lysate - whole (rat pituitary, mouse LbT2 cell line)
Gel Running Conditions
Non-reduced Denaturing (10%)
Loading amount
30 µg
Specification
rat pituitary, mouse LbT2 cell line
Blocking step
Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 6% · Temperature: 20°C
Username

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投稿 May 20 2015

Application
Western blot
Sample
Mouse Cell lysate - whole cell (LbetaT2 gonadotrope cell line)
Gel Running Conditions
Non-reduced Denaturing (10% SDS-PAGE)
Loading amount
30 µg
Specification
LbetaT2 gonadotrope cell line
Blocking step
Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 6% · Temperature: 20°C
Username

Abcam user community

Verified customer

投稿 May 20 2015

Vielen Dank für Ihre Antwort.
Wie besprochen wurde ab118757 bisher noch nicht in Maus getestet.
Falls Sie dies selbst testen möchten, kann ich Ihnen zurzeit ein spezielles Angebot über einen 100%igen Abreview-Rabatt anbieten. Bei diesem Angeb...

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Vielen Dank für das Telefongespräch gestern.
Ich möchte nochmals betonen wie leid es uns tut, dass ab75313 nicht in der von Ihnen gewünschten Menge lieferbar ist.
Leider haben wir keinen anderen GPCR GPR120 Antikörper, der für Maus getestet i...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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