製品の概要

  • 製品名Anti-GPCR GPR116 antibody
    GPCR GPR116 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to GPCR GPR116
  • アプリケーション適用あり: IHC-P, ICC/IFmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic peptide: V CYKHNFNA SS VSWCSKT VDV CCHFTN AANN SVWSP SMKLN LVPG ENITCQ, corresponding to amino acids 620-670 of Human GPCR GPR116

  • ポジティブ・コントロール
    • Human breast carcinoma tissue; A549 cells.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • バッファーpH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: 49.1% PBS, 50% Glycerol, 0.88% Sodium chloride
    Note: PBS (without Mg2+ and Ca2+)
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)ab111169 was affinity-purified from Rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab111169 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF 1/100 - 1/500.

ターゲット情報

  • 機能May have a role in the regulation of acid-base balance.
  • 配列類似性Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
    Contains 1 GPS domain.
    Contains 3 Ig-like (immunoglobulin-like) domains.
    Contains 1 SEA domain.
  • 翻訳後修飾Proteolytically cleaved into 2 highly conserved sites: one in the SEA domain and the other in the stalk domain region preceding the first transmembrane. The later 2 subunits, the extracellular subunit and the seven-transmembrane subunit, remain tightly associated and non-covalently linked.
  • 細胞内局在Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • DKFZp564O1923 antibody
    • FLJ90640 antibody
    • G protein coupled receptor 116 antibody
    • GP116_HUMAN antibody
    • GPR116 antibody
    • Ig Hepta homolog antibody
    • KIAA0758 antibody
    • KPG_001 antibody
    • OTTHUMP00000016557 antibody
    • Probable G protein coupled receptor 116 antibody
    • Probable G-protein coupled receptor 116 antibody
    see all

Anti-GPCR GPR116 antibody 画像

  • ab111169 at 1/50 dilution staining GPCR GPR116 in paraffin-embedded Human breast carcinoma tissue by Immunohistochemistry. The image on the right is treated with synthesized peptide.
  • ab111169 at 1/100 dilution staining GPCR GPR116 in A549 cells by Immunofluorescence. The image on the right is treated with synthesized peptide.

Anti-GPCR GPR116 antibody (ab111169) 使用論文

This product has been referenced in:
  • Tang X  et al. GPR116, an adhesion G-protein-coupled receptor, promotes breast cancer metastasis via the Gaq-p63RhoGEF-Rho GTPase pathway. Cancer Res 73:6206-18 (2013). IHC ; Human . Read more (PubMed: 24008316) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"