製品の概要

  • 製品名Goserelin peptide

製品の詳細

  • 由来Synthetic
  • アミノ酸配列
    • 配列 Glu-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-AzGly1- NH2.

特性

Our Abpromise guarantee covers the use of ab68486 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度> 95 % SDS-PAGE.
    Purity is greater than 98.0% as determined by analysis by RP-HPLC and SDS-PAGE.
  • 製品の状態Lyophilised
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None.
    No additives.

  • 再構成Reconstitute in sterile 18MOhms/cm water to not less than 100 µg/ml, (which can then be further diluted to other aqueous solutions.) For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).

関連情報

  • 別名
    • Goserelin acetate
    • Zoladex®
  • 関連性Goserelin is a synthetic decapeptide analogue of luteinising hormone-releasing hormone (LHRH). On administration, initially, goserelin causes an increase in the amount of FSH and LH released from the pituitary gland. However, chronic administration of goserelin desensitises the pituitary gland. Eventually, after a period of about 14-21 days, production of LH is greatly reduced due to receptor downregulation, and sex hormones levels are reduced. This reduction in the levels of sex hormone can be exploited to treat disorders that are linked to levels of oestrogen or testosterone; such as prostate cancer, oestrogen dependant breast cancer, endometriosis and other benign gynaecological disorders.
  • 細胞内局在Secreted

Goserelin peptide (ab68486) 使用論文

ab68486 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"