Anti-GNMT 抗体 - Carboxyterminal end (ab71460)

製品の概要

  • 製品名Anti-GNMT antibody - Carboxyterminal end
    GNMT 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to GNMT - Carboxyterminal end
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
  • ポジティブ・コントロール
    • CEM cell line lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab71460 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
  • 追加情報ELISA: 1/1000.
    WB: 1/100 - 1/500. Detects bands of approximately 30 and 34 kDa (predicted molecular weight: 33 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Catalyzes the methylation of glycine by using S-adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy). Possible crucial role in the regulation of tissue concentration of AdoMet and of metabolism of methionine.
    • 組織特異性Abundant in liver.
    • 関連疾患Defects in GNMT are the cause of glycine N-methyltransferase deficiency (GNMT deficiency) [MIM:606664]; also known as hypermethioninemia. The only clinical abnormalities in patients with this deficiency are mild hepatomegaly and chronic elevation of serum transaminases.
    • 配列類似性Belongs to the glycine N-methyltransferase family.
    • 細胞内局在Cytoplasm.
    • Information by UniProt
    • 参照データベース
    • 別名
      • EC 2.1.1.20 antibody
      • Glycine N methyltransferase antibody
      • Glycine N-methyltransferase antibody
      • Gnmt antibody
      • GNMT_HUMAN antibody
      • OTTHUMP00000016412 antibody
      see all

    Anti-GNMT antibody - Carboxyterminal end 画像

    • Anti-GNMT antibody - Carboxyterminal end (ab71460) at 1/60 dilution + CEM cell line lysate at 35 µg

      Predicted band size : 33 kDa
      Observed band size : 34 kDa (why is the actual band size different from the predicted?)
      Additional bands at : 30 kDa. We are unsure as to the identity of these extra bands.

    Anti-GNMT antibody - Carboxyterminal end (ab71460) 使用論文

    ab71460 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"