製品の概要

  • 製品名
  • 製品の詳細
    Goat polyclonal to GNB3
  • 特異性
    ab109466 is expected to recognize GNB3 and GNB4 (Gene ID: 2784, 59345; Protein ID: NP_002066.1; NP_067642.1).
  • アプリケーション
    適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic peptide:

    SGHDNRVSCLGVT

    , corresponding to internal sequence amino acids 309-321 of Human GNB3 (NP_002066.1).

  • ポジティブ・コントロール
    • HepG2 cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab109466 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 35 kDa (predicted molecular weight: 37 kDa).
IHC-P Use a concentration of 3 - 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能
    Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
  • 配列類似性
    Belongs to the WD repeat G protein beta family.
    Contains 7 WD repeats.
  • Information by UniProt
  • 参照データベース
  • 別名
    • G protein beta 3 subunit antibody
    • GBB3_HUMAN antibody
    • GNB3 antibody
    • GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 antibody
    • GTP binding regulatory protein beta 3 chain antibody
    • Guanine nucleotide binding protein (G protein) beta polypeptide 3 antibody
    • Guanine nucleotide binding protein G antibody
    • Guanine nucleotide binding protein G(I)/G(S)/G(T) beta subunit 3 antibody
    • Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 antibody
    • Hypertension associated protein antibody
    • IG antibody
    • SG antibody
    • Transducin beta chain 3 antibody
    • Tsubunit beta 3 antibody
    see all

画像

  • Anti-GNB3 antibody (ab109466) at 0.1 µg/ml + HepG2 cell lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 37 kDa
  • ab109466 (3.8µg/ml) staining of paraffin embedded Human Cerebellum shows strong axonal staining in the Molecular layer and less so in the Granular layer. Tissue treated: Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

参考文献

ab109466 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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