Anti-GM-CSF Receptor alpha 抗体 [4H1] (Phycoerythrin) (ab95683)

製品の概要

  • 製品名
    Anti-GM-CSF Receptor alpha antibody [4H1] (Phycoerythrin)
    GM-CSF Receptor alpha 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [4H1] to GM-CSF Receptor alpha (Phycoerythrin)
  • 標識
    Phycoerythrin. Ex: 488nm, Em: 575nm
  • アプリケーション
    適用あり: Flow Cytmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Human GM-CSF Receptor alpha transfected COS cells.

  • ポジティブ・コントロール
    • Normal human peripheral blood cells/leukocytes.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab95683 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt Use 5µl for 106 cells.

ターゲット情報

  • 機能
    Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells.
  • 関連疾患
    Defects in CSF2RA are the cause of pulmonary surfactant metabolism dysfunction type 4 (SMDP4) [MIM:300770]. A rare lung disorder due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress.
  • 配列類似性
    Belongs to the type I cytokine receptor family. Type 5 subfamily.
  • ドメイン
    The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
    The box 1 motif is required for JAK interaction and/or activation.
  • 細胞内局在
    Secreted and Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CD_antigen=CD116 antibody
    • CD116 antibody
    • CD116 antigen antibody
    • CDw116 antibody
    • Colony stimulating factor 2 receptor alpha chain antibody
    • Colony stimulating factor 2 receptor alpha low affinity antibody
    • Colony stimulating factor 2 receptor alpha subunit antibody
    • CSF 2R antibody
    • CSF2R antibody
    • CSF2R_HUMAN antibody
    • CSF2RA antibody
    • CSF2RAX antibody
    • CSF2RAY antibody
    • CSF2RX antibody
    • CSF2RY antibody
    • GM CSF R alpha antibody
    • GM CSF receptor alpha subunit antibody
    • GM-CSF-R-alpha antibody
    • GMCSFR antibody
    • GMCSFR-alpha antibody
    • GMR-alpha antibody
    • Granulocyte macrophage colony stimulating factor receptor alpha chain antibody
    • Granulocyte-macrophage colony-stimulating factor receptor subunit alpha antibody
    • SMDP4 antibody
    see all

画像

  • Flow cytometry staining of normal Human peripheral blood cells with Mouse IgG1 ? Isotype Control PE (open histogram) or 20µl ab95683 (filled histogram). Cells in the monocyte gate were used for analysis.

プロトコール

参考文献

ab95683 has not yet been referenced specifically in any publications.

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