Anti-GM-CSF Receptor alpha 抗体 [4H1] (FITC) (ab95684)

製品の概要

  • 製品名Anti-GM-CSF Receptor alpha antibody [4H1] (FITC)
    GM-CSF Receptor alpha 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [4H1] to GM-CSF Receptor alpha (FITC)
  • 標識FITC. Ex: 493nm, Em: 528nm
  • アプリケーション適用あり: Flow Cytmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Human GM-CSF Receptor alpha transfected COS cells.

  • ポジティブ・コントロール
    • Normal human peripheral blood cells/leukocytes.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab95684 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt Use 5µl for 106 cells.

ab106163 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

ターゲット情報

  • 機能Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells.
  • 関連疾患Defects in CSF2RA are the cause of pulmonary surfactant metabolism dysfunction type 4 (SMDP4) [MIM:300770]. A rare lung disorder due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress.
  • 配列類似性Belongs to the type I cytokine receptor family. Type 5 subfamily.
  • ドメインThe WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
    The box 1 motif is required for JAK interaction and/or activation.
  • 細胞内局在Secreted and Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CD_antigen=CD116 antibody
    • CD116 antibody
    • CD116 antigen antibody
    • CDw116 antibody
    • Colony stimulating factor 2 receptor alpha chain antibody
    • Colony stimulating factor 2 receptor alpha low affinity antibody
    • Colony stimulating factor 2 receptor alpha subunit antibody
    • CSF 2R antibody
    • CSF2R antibody
    • CSF2R_HUMAN antibody
    • CSF2RA antibody
    • CSF2RAX antibody
    • CSF2RAY antibody
    • CSF2RX antibody
    • CSF2RY antibody
    • GM CSF R alpha antibody
    • GM CSF receptor alpha subunit antibody
    • GM-CSF-R-alpha antibody
    • GMCSFR antibody
    • GMCSFR-alpha antibody
    • GMR-alpha antibody
    • Granulocyte macrophage colony stimulating factor receptor alpha chain antibody
    • Granulocyte-macrophage colony-stimulating factor receptor subunit alpha antibody
    • SMDP4 antibody
    see all

Anti-GM-CSF Receptor alpha antibody [4H1] (FITC) 画像

  • Flow cytometry staining of normal Human peripheral blood cells with Mouse IgG1 ? Isotype Control FITC (open histogram) or 20µl ab95684 (filled histogram). Cells in the monocyte gate were used for analysis.

Anti-GM-CSF Receptor alpha antibody [4H1] (FITC) (ab95684) 使用論文

ab95684 has not yet been referenced specifically in any publications.

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