GM 6001, MMP inhibitor (ab120845)
Key features and details
- Broad spectrum MMP inhibitor
- CAS Number: 142880-36-2
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
GM 6001, MMP inhibitor -
製品の詳細
Broad spectrum MMP inhibitor -
別名
- Galardin
- ilomastat
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精製度
> 98% -
CAS 番号
142880-36-2 -
構造式
製品の特性
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体系名
(2R)-N4-Hydroxy-N1-[(1S)-2-(1H-indol-3-ylmethyl)-2-(methylamino)-2-oxoethyl]-2-(2-methylpropyl)butanediamide -
分子量
388.47 -
分子式
C20H28N4O4 -
PubChem 登録番号
132519 -
保存方法
Store at +4°C. The product can be stored for up to 12 months. -
溶解性
Soluble in DMSO to 100 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further instruction.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
ONC(=O)C[C@@H](CC(C)C)C(=O)N[C@@H](Cc2cnc1ccccc12)C(=O)NC -
由来
Synthetic
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研究分野
関連製品
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Alternative Versions
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (16)
ab120845 は 16 報の論文で使用されています。
- Rolland L et al. The regenerative response of cardiac interstitial cells. J Mol Cell Biol 14:N/A (2023). PubMed: 36271843
- Sharick JT et al. Click chemistry functionalization of self-assembling peptide hydrogels. J Biomed Mater Res A 111:389-403 (2023). PubMed: 36210776
- Benn MC et al. How the mechanobiology orchestrates the iterative and reciprocal ECM-cell cross-talk that drives microtissue growth. Sci Adv 9:eadd9275 (2023). PubMed: 36989370
- Dedhia PH et al. A 3D adrenocortical carcinoma tumor platform for preclinical modeling of drug response and matrix metalloproteinase activity. Sci Rep 13:15508 (2023). PubMed: 37726363
- Yu Y et al. Changes to gut amino acid transporters and microbiome associated with increased E/I ratio in Chd8+/- mouse model of ASD-like behavior. Nat Commun 13:1151 (2022). PubMed: 35241668