Anti-Glypican 3 抗体 [SP86], prediluted (ab95364)

製品の概要

  • 製品名Anti-Glypican 3 antibody [SP86], prediluted
    Glypican 3 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [SP86] to Glypican 3, prediluted
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide derived from the C terminal of Human Glypican 3.

  • ポジティブ・コントロール
    • Human liver cancer tissue

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab95364 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use at an assay dependent concentration. Perform heat mediated antigen retrieval (boil tissue section in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min).

ターゲット情報

  • 機能Cell surface proteoglycan that bears heparan sulfate. Inhibits the dipeptidyl peptidase activity of DPP4. May be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs. May play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. May regulate growth and tumor predisposition.
  • 組織特異性Highly expressed in lung, liver and kidney.
  • 関連疾患Defects in GPC3 are the cause of Simpson-Golabi-Behmel syndrome type 1 (SGBS1) [MIM:312870]; also known as Simpson dysmorphia syndrome (SDYS). SGBS is a condition characterized by pre- and postnatal overgrowth (gigantism) with visceral and skeletal anomalies.
  • 配列類似性Belongs to the glypican family.
  • 細胞内局在Cell membrane and Secreted > extracellular space.
  • Information by UniProt
  • 参照データベース
  • 別名
    • DGSX antibody
    • Glypican proteoglycan 3 antibody
    • Glypican-3 [Precursor] antibody
    • Gpc3 antibody
    • GPC3_HUMAN antibody
    • GTR2 2 antibody
    • GTR2-2 antibody
    • Heparan sulphate proteoglycan antibody
    • Intestinal protein OCI 5 antibody
    • Intestinal protein OCI-5 antibody
    • MXR7 antibody
    • OCI 5 antibody
    • OCI-5 antibody
    • OCI5 antibody
    • SDYS antibody
    • Secreted glypican-3 antibody
    • SGB antibody
    • SGBS antibody
    • SGBS1 antibody
    see all

Anti-Glypican 3 antibody [SP86], prediluted 画像

  • Prediluted ab95364 staining Glypican 3 in formalin-fixed, paraffin-embedded Human liver cancer tissue by Immunohistochemistry.

Anti-Glypican 3 antibody [SP86], prediluted (ab95364) 使用論文

ab95364 has not yet been referenced specifically in any publications.

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