Anti-Glutamate Receptor 1 (AMPA subtype) (phospho S845) 抗体 (ab3901)


  • 製品名Anti-Glutamate Receptor 1 (AMPA subtype) (phospho S845) antibody
    Glutamate Receptor 1 (AMPA subtype) 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Glutamate Receptor 1 (AMPA subtype) (phospho S845)
  • 特異性ab3901 is specific for 100 kDa GluR1 phosphorylated at Ser845. Immunolabeling is blocked by the phosphopeptide but not by the dephosphopeptide.
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Rat
    交差が予測される動物種: Human
  • 免疫原

    Synthetic phosphopeptide corresponding to amino acid residues surrounding the phosphoSer845 of the GluR1 subunit of the AMPA subtype of glutamate receptor.



Our Abpromise guarantee covers the use of ab3901 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
  • 追加情報WB: 1/500 - 1/2000.

    By Western blot, this antibody detects a band of 100 kDa, which corresponds to the predicted molecular weight of phospho GluR 1.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist.
    • 組織特異性Widely expressed in brain.
    • 配列類似性Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIA1 subfamily.
    • 翻訳後修飾Palmitoylated. Depalmitoylated upon glutamate stimulation. Cys-603 palmitoylation leads to Golgi retention and decreased cell surface expression. In contrast, Cys-829 palmitoylation does not affect cell surface expression but regulates stimulation-dependent endocytosis.
    • 細胞内局在Cell membrane. Endoplasmic reticulum membrane. Cell junction > synapse > postsynaptic cell membrane. Interaction with CACNG2 promotes cell surface expression.
    • Information by UniProt
    • 参照データベース
    • 別名
      • GLUR 1 antibody
      • GLUR A antibody
      • AMPA 1 antibody
      • AMPA selective glutamate receptor 1 antibody
      • AMPA-selective glutamate receptor 1 antibody
      • GluA1 antibody
      • GLUH1 antibody
      • GluR K1 antibody
      • GluR-1 antibody
      • GluR-A antibody
      • GluR-K1 antibody
      • GLUR1 antibody
      • GLURA antibody
      • GluRK1 antibody
      • Glutamate receptor 1 antibody
      • Glutamate receptor ionotropic AMPA 1 antibody
      • Glutamate receptor ionotropic antibody
      • Glutamate receptor, ionotropic, AMPA 1 antibody
      • Gria1 antibody
      • GRIA1_HUMAN antibody
      • HBGR1 antibody
      • MGC133252 antibody
      • OTTHUMP00000160643 antibody
      • OTTHUMP00000165781 antibody
      • OTTHUMP00000224241 antibody
      • OTTHUMP00000224242 antibody
      • OTTHUMP00000224243 antibody
      see all

    Anti-Glutamate Receptor 1 (AMPA subtype) (phospho S845) antibody (ab3901) 使用論文

    This product has been referenced in:
    • Castilho AF  et al. Diabetes causes transient changes in the composition and phosphorylation of a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors and interaction with auxiliary proteins in the rat retina. Mol Vis 20:894-907 (2014). WB ; Rat . Read more (PubMed: 24966661) »
    • Hinard V  et al. Key electrophysiological, molecular, and metabolic signatures of sleep and wakefulness revealed in primary cortical cultures. J Neurosci 32:12506-17 (2012). WB ; Mouse . Read more (PubMed: 22956841) »

    See all 5 Publications for this product

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