製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to GLUT9
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Horse, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide: VVTVIVTMAC YQLCGLNAIW FYTNSIFGKA GIPPAKIPYV TLSTGGIETL , corresponding to internal sequence amino acids 288 - 337 of Human GLUT9(Peptide available as ab105952.)

  • ポジティブ・コントロール
    • HepG2 cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab82910 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 59 kDa.Can be blocked with GLUT9 peptide (ab105952). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能
    Transport urate and fructose. May have a role in the urate reabsorption by proximal tubules. Also transports glucose at low rate.
  • 組織特異性
    Most strongly expressed in basolateral membranes of proximal renal tubular cells, liver and placenta. Also detected in lung, blood leukocytes, heart skeletal muscle and chondrocytes from articular cartilage. Isoform 2 is only detected in the apical membranes of polarized renal tubular cells and placenta. Isoform 1 and isoform 2 are detected in kidney membrane (at protein level).
  • 関連疾患
    Hypouricemia renal 2
  • 配列類似性
    Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
  • 細胞内局在
    Basolateral cell membrane and Apical cell membrane. Basolateral cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • glucose transporter 9 antibody
    • Glucose transporter like protein 9 antibody
    • Glucose transporter type 9 antibody
    • GLUT 9 antibody
    • GLUT-9 antibody
    • GLUT9 antibody
    • GLUTX antibody
    • GTR9_HUMAN antibody
    • Human glucose transporter like protein 9 antibody
    • SLC2A9 antibody
    • Solute carrier family 2 (facilitated glucose transporter) member 9 antibody
    • Solute carrier family 2 facilitated glucose transporter member 9 antibody
    • Solute carrier family 2 member 9 antibody
    • Solute carrier family 2 member 9 protein antibody
    • Solute carrier family 2, facilitated glucose transporter member 9 antibody
    • UAQTL2 antibody
    • Urate voltage driven efflux transporter 1 antibody
    • URATv1 antibody
    see all

画像

  • Anti-GLUT9 antibody (ab82910) at 1 µg/ml (5% skim milk / PBS buffer) + HepG2 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 59 kDa
    Observed band size : 59 kDa

プロトコール

参考文献

This product has been referenced in:
  • Karim S  et al. Dysregulated hepatic expression of glucose transporters in chronic disease: contribution of semicarbazide-sensitive amine oxidase to hepatic glucose uptake. Am J Physiol Gastrointest Liver Physiol 307:G1180-90 (2014). Read more (PubMed: 25342050) »
  • Gaccioli F  et al. Maternal overweight induced by a diet with high content of saturated fat activates placental mTOR and eIF2 alpha signaling and increases fetal growth in rats. Biol Reprod 89:96 (2013). Rat . Read more (PubMed: 24006279) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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