製品の概要

  • 製品名
    Anti-GLUD1 antibody (HRP)
    GLUD1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to GLUD1 (HRP)
  • 標識
    HRP
  • 特異性
    Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-peroxidase, anti-Rabbit Serum as well as purified and partially purified Glutamate Dehydrogenase [Bovine Liver].Cross reactivity from other tissues and species may occur but have not been determined. Due to high sequence homology with GLUD2 there is a potential for cross-reactivity.
  • アプリケーション
    適用あり: ELISAmore details
  • 種交差性
    交差種: Cow
  • 免疫原

    Tissue, cells or virus corresponding to Cow GLUD1. Bovine liver Glutamate Dehydrogenase.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab21142 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA
  • 追加情報
    Assayed against 1.0ug of Glutamate Dehydrogenase (Bovine Liver) in a standard capture ELISA using ABTS as a substrate for 30 minutes at room temperature.
    ELISA: 1/1000 - 1/3900.
    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate.
    • 関連疾患
      Defects in GLUD1 are the cause of familial hyperinsulinemic hypoglycemia type 6 (HHF6) [MIM:606762]; also known as hyperinsulinism-hyperammonemia syndrome (HHS). Familial hyperinsulinemic hypoglycemia [MIM:256450], also referred to as congenital hyperinsulinism, nesidioblastosis, or persistent hyperinsulinemic hypoglycemia of infancy (PPHI), is the most common cause of persistent hypoglycemia in infancy and is due to defective negative feedback regulation of insulin secretion by low glucose levels. In HHF6 elevated oxidation rate of glutamate to alpha-ketoglutarate stimulates insulin secretion in the pancreatic beta cells, while they impair detoxification of ammonium in the liver.
    • 配列類似性
      Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    • 細胞内局在
      Mitochondrion matrix.
    • Information by UniProt
    • 参照データベース
    • 別名
      • AI118167 antibody
      • DHE3_HUMAN antibody
      • EC 1.4.1.3 antibody
      • GDH 1 antibody
      • GDH antibody
      • Gdh-X antibody
      • GDH1 antibody
      • GLUD antibody
      • Glud1 antibody
      • Glud1a antibody
      • Glud1b antibody
      • Gludl antibody
      • Glutamate dehydrogenase (NAD(P)+) antibody
      • Glutamate dehydrogenase 1 antibody
      • Glutamate dehydrogenase 1 mitochondrial antibody
      • Glutamate dehydrogenase 1a antibody
      • Glutamate dehydrogenase 1b antibody
      • Memory-related gene 2 protein antibody
      • MGC127177 antibody
      • MGC132003 antibody
      • MGC80801 antibody
      • MGC93608 antibody
      • mitochondrial antibody
      • MRG-2 antibody
      see all

    Anti-GLUD1 antibody (HRP) (ab21142) 使用論文

    ab21142 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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