製品の概要

  • 製品名Anti-GLUD1 antibody (Biotin)
    GLUD1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to GLUD1 (Biotin)
  • 標識Biotin
  • 特異性Due to high sequence homology with GLUD2 there is a potential for cross-reactivity.
  • アプリケーション適用あり: Dot blot, WB, ELISA, Immunomicroscopymore details
  • 種交差性
    交差種: Cow
  • 免疫原

    Full length native protein (purified) corresponding to Cow GLUD1. Full length native protein from Bovine Liver.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab34810 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Dot blot
WB
ELISA
Immunomicroscopy
  • 追加情報Dot: Use at an assay dependent dilution.
    ELISA: 1/4,000 - 1/20,000.
    IM: Use at an assay dependent dilution.
    WB: Use at an assay dependent dilution. Predicted molecular weight: 62 kDa.

    This product has been assayed against 1.0 µg of Glutamate Dehydrogenase in a standard capture ELISA using Peroxidase Conjugated Streptavidin and ABTS as a substrate for 30 minutes at room temperature.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate.
    • 関連疾患Defects in GLUD1 are the cause of familial hyperinsulinemic hypoglycemia type 6 (HHF6) [MIM:606762]; also known as hyperinsulinism-hyperammonemia syndrome (HHS). Familial hyperinsulinemic hypoglycemia [MIM:256450], also referred to as congenital hyperinsulinism, nesidioblastosis, or persistent hyperinsulinemic hypoglycemia of infancy (PPHI), is the most common cause of persistent hypoglycemia in infancy and is due to defective negative feedback regulation of insulin secretion by low glucose levels. In HHF6 elevated oxidation rate of glutamate to alpha-ketoglutarate stimulates insulin secretion in the pancreatic beta cells, while they impair detoxification of ammonium in the liver.
    • 配列類似性Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    • 細胞内局在Mitochondrion matrix.
    • Information by UniProt
    • 参照データベース
    • 別名
      • AI118167 antibody
      • DHE3_HUMAN antibody
      • EC 1.4.1.3 antibody
      • GDH 1 antibody
      • GDH antibody
      • Gdh-X antibody
      • GDH1 antibody
      • GLUD antibody
      • Glud1 antibody
      • Glud1a antibody
      • Glud1b antibody
      • Gludl antibody
      • Glutamate dehydrogenase (NAD(P)+) antibody
      • Glutamate dehydrogenase 1 antibody
      • Glutamate dehydrogenase 1 mitochondrial antibody
      • Glutamate dehydrogenase 1a antibody
      • Glutamate dehydrogenase 1b antibody
      • Memory-related gene 2 protein antibody
      • MGC127177 antibody
      • MGC132003 antibody
      • MGC80801 antibody
      • MGC93608 antibody
      • mitochondrial antibody
      • MRG-2 antibody
      see all

    Anti-GLUD1 antibody (Biotin) (ab34810) 使用論文

    ab34810 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab34810.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"