Anti-Glucose 6 phosphate isomerase 抗体 (ab110051)

製品の概要

  • 製品名Anti-Glucose 6 phosphate isomerase antibody
    Glucose 6 phosphate isomerase 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to Glucose 6 phosphate isomerase
  • アプリケーション適用あり: ELISA, WB, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Pig, Cynomolgus Monkey
  • 免疫原

    Synthetic peptide (

    C-YREHRSELNLRR

    ) corresponding to internal sequence amino acids 17-28 of Human Glucose 6 phosphate isomerase.

  • ポジティブ・コントロール
    • Human Kidney, Testis and Thyroid tissue. Human Heart lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab110051 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/128000.
WB Use a concentration of 0.01 - 0.03 µg/ml. Detects a band of approximately 60 kDa (predicted molecular weight: 63 kDa).
IHC-P Use a concentration of 3.75 µg/ml.

ターゲット情報

  • 機能Besides it's role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons.
  • パスウェイCarbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4.
  • 関連疾患Defects in GPI are the cause of hemolytic anemia non-spherocytic due to glucose phosphate isomerase deficiency (HA-GPID) [MIM:613470]. It is a form of anemia in which there is no abnormal hemoglobin or spherocytosis. It is caused by glucose phosphate isomerase deficiency. Severe GPI deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.
  • 配列類似性Belongs to the GPI family.
  • 翻訳後修飾Phosphorylation at Ser-185 by CK2 has been shown to decrease enzymatic activity and may contribute to secretion by a non-classical secretory pathway.
    ISGylated.
  • 細胞内局在Cytoplasm. Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • AMF antibody
    • Aurocrine motility factor antibody
    • Autocrine motility factor antibody
    • DKFZp686C13233 antibody
    • EC 5.3.1.9 antibody
    • G6PI_HUMAN antibody
    • Glucose phosphate isomerase antibody
    • Glucose-6-phosphate isomerase antibody
    • GNPI antibody
    • GPI antibody
    • Gpi1 antibody
    • Hexose monophosphate isomerase antibody
    • Hexosephosphate isomerase antibody
    • Neuroleukin antibody
    • NLK antibody
    • Oxoisomerase antibody
    • PGI antibody
    • PHI antibody
    • Phosphoglucose isomerase antibody
    • Phosphohexomutase antibody
    • Phosphohexose isomerase antibody
    • Phosphosaccharomutase antibody
    • SA 36 antibody
    • SA-36 antibody
    • SA36 antibody
    • Sperm antigen 36 antibody
    see all

Anti-Glucose 6 phosphate isomerase antibody 画像

  • Anti-Glucose 6 phosphate isomerase antibody (ab110051) at 0.01 µg/ml + Human Heart lysate in RIPA buffer at 35 µg
    Developed using the ECL technique

    Predicted band size : 63 kDa
  • ab110051 at 3.75 µg/ml staining Glucose 6 phosphate isomerase in Formalin-Fixed, Paraffin-Embedded Human Kidney by Immunohistochemistry.
  • ab110051 at 3.75 µg/ml staining Glucose 6 phosphate isomerase in Formalin-Fixed, Paraffin-Embedded Human Testis by Immunohistochemistry.
  • ab110051 at 3.75 µg/ml staining Glucose 6 phosphate isomerase in Formalin-Fixed, Paraffin-Embedded Human Thyroid by Immunohistochemistry.

Anti-Glucose 6 phosphate isomerase antibody (ab110051) 使用論文

ab110051 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"