Anti-Glucose 6 Phosphate Dehydrogenase 抗体 [EPR6291] (ab124738)

製品の概要

  • 製品名Anti-Glucose 6 Phosphate Dehydrogenase antibody [EPR6291]
    Glucose 6 Phosphate Dehydrogenase 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EPR6291] to Glucose 6 Phosphate Dehydrogenase
  • アプリケーション適用あり: WB, Flow Cytmore details
    適用なし: ICC,IHC-P or IP
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Synthetic peptide, corresponding to residues in Human Glucose 6 Phosphate Dehydrogenase.

  • ポジティブ・コントロール
    • 293T, MOLT4, HUVEC and HeLa cell lysates; Permeablized HeLa cells.
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab124738 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/10000 - 1/50000. Detects a band of approximately 59 kDa (predicted molecular weight: 59 kDa).
Flow Cyt 1/10 - 1/100. ab172730-Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
  • 追加情報Is unsuitable for ICC,IHC-P or IP.
  • ターゲット情報

    • 機能Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis.
    • 組織特異性Isoform Long is found in lymphoblasts, granulocytes and sperm.
    • パスウェイCarbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.
    • 関連疾患Anemia, non-spherocytic hemolytic, due to G6PD deficiency
    • 配列類似性Belongs to the glucose-6-phosphate dehydrogenase family.
    • 翻訳後修飾Acetylated by ELP3 at Lys-403; acetylation inhibits its homodimerization and enzyme activity. Deacetylated by SIRT2 at Lys-403; deacetylation stimulates its enzyme activity.
    • Information by UniProt
    • 参照データベース
    • 別名
      • G6PD antibody
      • G6PD_HUMAN antibody
      • G6PD1 antibody
      • G6pdx antibody
      • Glucose 6 phosphate 1 dehydrogenase antibody
      • Glucose 6 phosphate dehydrogenase antibody
      • Glucose 6 phosphate dehydrogenase, G6PD antibody
      • Glucose-6-phosphate 1-dehydrogenase antibody
      • MET19 antibody
      • POS10 antibody
      • Zwf1p antibody
      see all

    Anti-Glucose 6 Phosphate Dehydrogenase antibody [EPR6291] 画像

    • All lanes : Anti-Glucose 6 Phosphate Dehydrogenase antibody [EPR6291] (ab124738) at 1/10000 dilution

      Lane 1 : 293T cell lysate
      Lane 2 : MOLT4 cell lysate
      Lane 3 : HUVEC cell lysate
      Lane 4 : HeLa cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      Goat anti-Rabbit HRP at 1/2000 dilution

      Predicted band size : 59 kDa
    • ab124738 at 1/10 dilution staining Glucose 6 Phosphate Dehydrogenase in permeablized HeLa cells (red) or a rabbit IgG (negative) (green).

    Anti-Glucose 6 Phosphate Dehydrogenase antibody [EPR6291] (ab124738) 使用論文

    ab124738 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab124738.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"