Wang G et al.Human amniotic epithelial cells regulate osteoblast differentiation through the secretion of TGFß1 and microRNA-34a-5p.Int J Mol Med 41:791-799 (2018).
ICC/IF
;
Human
.
PubMed: 29207015
Sheets TP et al.Targeted Mutation of NGN3 Gene Disrupts Pancreatic Endocrine Cell Development in Pigs.Sci Rep 8:3582 (2018).
PubMed: 29483633
Huang WQ et al.Abnormal CFTR Affects Glucagon Production by Islet a Cells in Cystic Fibrosis and Polycystic Ovarian Syndrome.Front Physiol 8:835 (2017).
PubMed: 29204121
Harrington S et al.Improved yield of canine islet isolation from deceased donors.BMC Vet Res 13:264 (2017).
PubMed: 28830425
Dai C et al.Age-dependent human ß cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling.J Clin Invest 127:3835-3844 (2017).
PubMed: 28920919
Furukawa S et al.Databases for technical aspects of immunohistochemistry.J Toxicol Pathol 30:79-107 (2017).
IHC
;
Monkey
.
PubMed: 28190929
Lau J et al.Small Mouse Islets Are Deficient in Glucagon-Producing Alpha Cells but Rich in Somatostatin-Secreting Delta Cells.J Diabetes Res 2016:4930741 (2016).
IHC-P
;
Mouse
.
PubMed: 27504459
Gao Z et al.Male Men1 heterozygous mice exhibit fasting hyperglycemia in the early stage of MEN1.J Endocrinol 230:347-55 (2016).
PubMed: 27432891
Long AJ et al.Syk Inhibition Induces Platelet Dependent Peri-islet Hemorrhage in the Rat Pancreas.Toxicol Pathol 44:998-1012 (2016).
PubMed: 27324990
Woodland DC et al.Short-term high-fat feeding induces islet macrophage infiltration and ß-cell replication independently of insulin resistance in mice.Am J Physiol Endocrinol Metab 311:E763-E771 (2016).
PubMed: 27577853
Shirakawa J et al.DPP-4 inhibition improves early mortality, ß cell function, and adipose tissue inflammation in db/db mice fed a diet containing sucrose and linoleic acid.Diabetol Metab Syndr 8:16 (2016).
PubMed: 26937254
Kuroda Y et al.Osteoprotegerin Regulates Pancreatic ß-Cell Homeostasis upon Microbial Invasion.PLoS One 11:e0146544 (2016).
IHC
.
PubMed: 26751951
McCommis KS et al.An ancestral role for the mitochondrial pyruvate carrier in glucose-stimulated insulin secretion.Mol Metab 5:602-14 (2016).
PubMed: 27656398
Jacovetti C et al.Postnatal ß-cell maturation is associated with islet-specific microRNA changes induced by nutrient shifts at weaning.Nat Commun 6:8084 (2015).
ICC, IHC
.
PubMed: 26330140
Sharivkin R et al.Functional proteomics screen enables enrichment of distinct cell types from human pancreatic islets.PLoS One 10:e0115100 (2015).
Flow Cyt
.
PubMed: 25706282
Jafarian A et al.The Generation of Insulin Producing Cells from Human Mesenchymal Stem Cells by MiR-375 and Anti-MiR-9.PLoS One 10:e0128650 (2015).
IF
.
PubMed: 26047014
Patel A et al.RCAN1 links impaired neurotrophin trafficking to aberrant development of the sympathetic nervous system in Down syndrome.Nat Commun 6:10119 (2015).
Mouse
.
PubMed: 26658127
Shields EJ et al.Extreme Beta-Cell Deficiency in Pancreata of Dogs with Canine Diabetes.PLoS One 10:e0129809 (2015).
IHC
;
Dog
.
PubMed: 26057531
Coelho PA et al.Over-expression of Plk4 induces centrosome amplification, loss of primary cilia and associated tissue hyperplasia in the mouse.Open Biol 5:N/A (2015).
PubMed: 26701933
Bowerman M et al.Defects in pancreatic development and glucose metabolism in SMN-depleted mice independent of canonical spinal muscular atrophy neuromuscular pathology.Hum Mol Genet N/A:N/A (2014).
Mouse
.
PubMed: 24497575
Fløyel T et al.CTSH regulates ß-cell function and disease progression in newly diagnosed type 1 diabetes patients.Proc Natl Acad Sci U S A 111:10305-10 (2014).
IHC-P
;
Human, Mouse
.
PubMed: 24982147
Ahlgren KM et al.Lack of evidence for a role of islet autoimmunity in the aetiology of canine diabetes mellitus.PLoS One 9:e105473 (2014).
IHC-P
;
Dog
.
PubMed: 25153886
Lelliott CJ et al.Monoclonal antibody targeting of fibroblast growth factor receptor 1c ameliorates obesity and glucose intolerance via central mechanisms.PLoS One 9:e112109 (2014).
IHC
.
PubMed: 25427253
Novikova L et al.Variations in rodent models of type 1 diabetes: islet morphology.J Diabetes Res 2013:965832 (2013).
IHC-P
;
Human
.
PubMed: 23762878
Schwasinger-Schmidt T et al.Long-term liraglutide treatment is associated with increased insulin content and secretion in ß-cells, and a loss of a-cells in ZDF rats.Pharmacol Res 76:58-66 (2013).
IHC-P
;
Rat
.
PubMed: 23891763
Wittig C et al.Incorporation of bone marrow cells in pancreatic pseudoislets improves posttransplant vascularization and endocrine function.PLoS One 8:e69975 (2013).
IHC-P
.
PubMed: 23875013
Welker S et al.Glucose regulates protein kinase CK2 in pancreatic ß-cells and its interaction with PDX-1.Int J Biochem Cell Biol 45:2786-95 (2013).
IHC-Fr
;
Mouse
.
PubMed: 24126110
Pérez RJ et al.Deletion of retinoic acid receptor ß (RARß) impairs pancreatic endocrine differentiation.Exp Cell Res 319:2196-204 (2013).
IF
.
PubMed: 23756134
Ko SB et al.Inflammation increases cells expressing ZSCAN4 and progenitor cell markers in the adult pancreas.Am J Physiol Gastrointest Liver Physiol 304:G1103-16 (2013).
IF, IHC
.
PubMed: 23599043
Nollevaux MC et al.Characterization of ß-cell plasticity mechanisms induced in mice by a transient source of exogenous insulin.Am J Physiol Endocrinol Metab 304:E711-23 (2013).
IHC
.
PubMed: 23403947
Farmer K et al.KU-32, a novel drug for diabetic neuropathy, is safe for human islets and improves in vitro insulin secretion and viability.Exp Diabetes Res 2012:671673 (2012).
IHC-P
;
Mouse
.
PubMed: 23197975
Mohanasundaram D et al.Ultrastructural analysis, zinc transporters, glucose transporters and hormones expression in new world primate (Callithrix jacchus) and human pancreatic islets.Gen Comp Endocrinol : (2011).
IHC-Fr
;
Human, Common marmoset, Pig
.
PubMed: 21821034
Kakabadze Z et al.Long-term engraftment and function of transplanted pancreatic islets in vascularized segments of small intestine.Transpl Int 24:175-83 (2011).
PubMed: 20819197
Thatava T et al.Indolactam V/GLP-1-mediated differentiation of human iPS cells into glucose-responsive insulin-secreting progeny.Gene Ther 18:283-93 (2011).
IF
.
PubMed: 21048796
Huang HH et al.Exercise increases insulin content and basal secretion in pancreatic islets in type 1 diabetic mice.Exp Diabetes Res 2011:481427 (2011).
IF
.
PubMed: 21912535
Lu J et al.Alpha cell-specific Men1 ablation triggers the transdifferentiation of glucagon-expressing cells and insulinoma development.Gastroenterology 138:1954-65 (2010).
ICC/IF, IHC-P
;
Mouse
.
PubMed: 20138042
Gonzalez R et al.Pancreatic beta cells colocalize insulin and pronesfatin immunoreactivity in rodents.Biochem Biophys Res Commun 381:643-8 (2009).
IHC-P
;
Mouse, Rat
.
PubMed: 19248766
Shu L et al.Decreased TCF7L2 protein levels in type 2 diabetes mellitus correlate with downregulation of GIP- and GLP-1 receptors and impaired beta-cell function.Hum Mol Genet 18:2388-99 (2009).
IHC-P
;
Human
.
PubMed: 19386626
Peterson RA et al.Applications of laser scanning cytometry in immunohistochemistry and routine histopathology.Toxicol Pathol 36:117-32 (2008).
IHC-P
;
Rat
.
PubMed: 18337230
Hanley S & Rosenberg L Transforming growth factor beta is a critical regulator of adult human islet plasticity.Mol Endocrinol 21:1467-77 (2007).
IHC
;
Human
.
PubMed: 17405902
Witt S et al.[Production and use of monoclonal glucagon and insulin antibodies--reduction of pancreatic insulin in rats by treatment with complete Freund's adjuvant].Acta Histochem Suppl 35:217-23 (1988).
IHC
;
Rat
.
PubMed: 3138717
Farhat B et al.Small human islets comprised of more ß-cells with higher insulin content than large islets.Islets 5:87-94 (0).
IF
.
PubMed: 23648896
Huang HH et al.Low insulin content of large islet population is present in situ and in isolated islets.Islets 3:6-13 (0).
PubMed: 21325888
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