Rabbit polyclonal to GLRB
Synthetic peptide conjugated to KLH, corresponding to a region within N terminal amino acids 102-132 of Human GLRB (NP_001159532.1, NP_000815.1).
Mouse cerebellum tissue lysate
Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
Preservative: 0.09% Sodium azide
Constituent: 99% PBS
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Immunogen affinity purified
ab123886 is purified through a protein A column, followed by peptide affinity purification.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/500. Predicted molecular weight: 56 kDa.
GLRB (Glycine receptor beta) is a neurotransmitter-gated ion channel concentrated within the spinal cord and brainstem. Expression is also observed in several upper brain regions including the cortex, cerebellum, hippocampus and amygdala. Binding of glycine to GLRB increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing), controlling spinal reflexes and locomotor behavior.
Plasma membrane; multi-pass membrane protein.
Glycine receptor 58 kDa subunit antibody
Glycine receptor beta antibody
Glycine receptor subunit beta antibody
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"