製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to GJA3
  • アプリケーション
    適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide derived from an internal sequence of Human GJA3.

  • ポジティブ・コントロール
    • Human lung carcinoma tissue

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • バッファー
    pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: PBS, 0.88% Sodium chloride, 50% Glycerol
    Note: PBS (without Mg2+ and Ca2+)
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • 特記事項(精製)
    ab110894 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab110894 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能
    One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
  • 関連疾患
    Defects in GJA3 are the cause of cataract zonular pulverulent cataract type 3 (CZP3) [MIM:601885]. A form of zonular cataract. Zonular or lamellar cataracts are opacities, broad or narrow, usually consisting of powdery white dots affecting only certain layers or zones between the cortex and nucleus of an otherwise clear lens. The opacity may be so dense as to render the entire central region of the lens completely opaque, or so translucent that vision is hardly if at all impeded. Zonular cataracts generally do not involve the embryonic nucleus, though sometimes they involve the fetal nucleus. Usually sharply separated from a clear cortex outside them, they may have projections from their outer edges known as riders or spokes.
  • 配列類似性
    Belongs to the connexin family. Alpha-type (group II) subfamily.
  • 細胞内局在
    Cell membrane. Cell junction > gap junction.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CAE3 antibody
    • Connexin 46 antibody
    • Connexin-46 antibody
    • Connexin46 antibody
    • Cx46 antibody
    • CXA3_HUMAN antibody
    • CZP3 antibody
    • Gap junction alpha 3 protein antibody
    • Gap junction alpha-3 protein antibody
    • Gap junction protein, alpha 3, 46kD (connexin 46) antibody
    • Gap junction protein, alpha 3, 46kDa (connexin 46) antibody
    • Gap junction protein, alpha 3, 46kDa antibody
    • Gja3 antibody
    see all

Anti-GJA3 antibody 画像

  • ab110894, at a 1/50 dilution, staining GJA3 in paraffin-embedded Human Lung carcinoma tissue by Immunohistochemistry. The image on the right is treated with the synthesized peptide.

プロトコール

Anti-GJA3 antibody (ab110894) 使用論文

ab110894 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab110894.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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