製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to GIRK1
  • アプリケーション
    適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Guinea pig
  • 免疫原

    Recombinant fragment, corresponding to a region within amino acids 248-501 of Human GIRK1.

  • ポジティブ・コントロール
    • A431, H1299, HeLa whole cells lysate, DU145 xenograft

法規制情報

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab96168 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 57 kDa.
IHC-P 1/100 - 1/500.

ターゲット情報

  • 機能
    This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.
  • 配列類似性
    Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.
  • 細胞内局在
    Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • G protein activated inward rectifier potassium channel 1 antibody
    • G protein-activated inward rectifier potassium channel 1 antibody
    • GIRK-1 antibody
    • GIRK1 antibody
    • Inward rectifier K(+) channel Kir3.1 antibody
    • Inwardly rectifying potassium channel KIR3.1 antibody
    • inwardly rectifying subfamily J member 3 antibody
    • IRK3 antibody
    • IRK3_HUMAN antibody
    • Kcnf3 antibody
    • Kcnj3 antibody
    • KGA antibody
    • KGB1 antibody
    • Kir3.1 antibody
    • Potassium channel antibody
    • Potassium channel, inwardly rectifying subfamily J member 3 antibody
    • Potassium inwardly-rectifying channel, subfamily J, member 3 antibody
    see all

画像

  • All lanes : Anti-GIRK1 antibody (ab96168) at 1/1000 dilution

    Lane 1 : A431 whole cell lysate
    Lane 2 : H1299 whole cell lysate
    Lane 3 : HeLa whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 57 kDa
  • Immunohistochemical analysis of paraffin-embedded DU145 xenograft, using ab96168 at 1:100 dilution.

参考文献

ab96168 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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