Anti-GilZ / TilZ 抗体 [3A5] (ab117085)


  • 製品名Anti-GilZ / TilZ antibody [3A5]
    GilZ / TilZ 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [3A5] to GilZ / TilZ
  • アプリケーション適用あり: WB, IHC-P, ICC/IF, Sandwich ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 1-98 of Human GilZ/ TilZ with a proprietary tag (NP_932174).

  • ポジティブ・コントロール
    • Human breast and tonsil tissues; Transfected 293T lysate; HeLa cells.



Our Abpromise guarantee covers the use of ab117085 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Predicted molecular weight: 15 kDa.
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF Use a concentration of 10 µg/ml.
Sandwich ELISA Use at an assay dependent concentration.


  • 機能Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation. In vitro, suppresses AP1 and NFKB1 DNA-binding activities.
  • 組織特異性Expressed in brain, lung, spleen and skeletal muscle. Lower levels detected in heart and kidney. Not detected in the pancreas. In non-lymphoid tissues, in the absence of inflammation, the major source of constitutive expression is the macrophage lineage. Also expressed in cells from different hemopoietic cell lineages, including bone marrow cells, CD34+ stem cells, mature B- and T-cells, monocytes and granulocytes. Down-regulated in activated macrophages from inflammatory lesions of delayed-type hypersensitivity (DTH) reactions, such as in tuberculosis and in Crohn disease, whereas in Burkitt lymphoma, persists in macrophages involved in the phagocytosis of apoptotic malignant cells.
  • 配列類似性Belongs to the TSC-22/Dip/Bun family.
  • ドメインThe leucine-zipper is involved in homodimerization.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Delta sleep-inducing peptide immunoreactor antibody
    • DIP antibody
    • DSIP immunoreactive leucine zipper protein antibody
    • DSIP-immunoreactive peptide antibody
    • Dsip1 antibody
    • Dsipi antibody
    • GILZ antibody
    • Glucocorticoid-induced leucine zipper protein antibody
    • hDIP antibody
    • Protein DIP antibody
    • T22D3_HUMAN antibody
    • TSC-22-like protein antibody
    • TSC-22-related protein antibody
    • TSC-22R antibody
    • TSC22 domain family protein 3 antibody
    • TSC22 domain family, member 3 antibody
    • TSC22 related inducible leucine zipper 3 antibody
    • TSC22D3 antibody
    see all

Anti-GilZ / TilZ antibody [3A5] 画像

  • ab117085, at 5 µg/ml, staining GilZ / TilZ in Formalin-fixed, Paraffin-embedded Human Breast tissue by Immunohistochemistry.
  • ab117085, at 5 µg/ml, staining GilZ / TilZ in Formalin-fixed, Paraffin-embedded Human Tonsil tissue by Immunohistochemistry.
  • All lanes : Anti-GilZ / TilZ antibody [3A5] (ab117085)

    Lane 1 : 293T cell lysate, transfected with GilZ / TilZ
    Lane 2 : 293T cell lysate, non transfected

    Predicted band size : 15 kDa
  • ab117085 at 10µg/ml dilution staining GilZ / TilZ in HeLa cells by Immunofluorescence.
  • Detection limit for recombinant tagged ab117085 is approximately 0.03 ng/ml as a capture antibody.

Anti-GilZ / TilZ antibody [3A5] (ab117085) 使用論文

ab117085 has not yet been referenced specifically in any publications.

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample Human Tissue sections (Burkitt's lymphoma cell line xenograft)
Antigen retrieval step Heat mediated - Buffer/Enzyme Used: NaCitrate pH 6
Permeabilization No
Specification Burkitt's lymphoma cell line xenograft
Blocking step Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 15% · Temperature: 20°C
Fixative Formaldehyde

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投稿 Dec 21 2015

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