製品の概要

  • 製品名Anti-GFM1 antibody
    GFM1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to GFM1
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    A KLH conjugated synthetic peptide between C terminal amino acids 727-755 of Human GFM1 (NP_079272.4).

  • ポジティブ・コントロール
    • WB: NCI-H460 cell line lysates; Mouse heart tissue lysates IHC-P: Human bladder carcinoma

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab107496 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 83 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis.
  • パスウェイProtein biosynthesis; polypeptide chain elongation.
  • 関連疾患Defects in GFM1 are the cause of combined oxidative phosphorylation deficiency type 1 (COXPD1) [MIM:609060]. It leads to early fatal progressive hepatoencephalopathy.
  • 配列類似性Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.
  • 細胞内局在Mitochondrion.
  • Information by UniProt
  • 参照データベース
  • 別名
    • COXPD1 antibody
    • EF-Gmt antibody
    • EFG antibody
    • EFG1 antibody
    • EFGM antibody
    • EFGM_HUMAN antibody
    • EGF1 antibody
    • Elongation factor G 1 antibody
    • Elongation factor G 1 mitochondrial antibody
    • Elongation factor G antibody
    • Elongation factor G1 antibody
    • FLJ12662 antibody
    • FLJ13632 antibody
    • FLJ20773 antibody
    • G elongation factor mitochondrial 1 antibody
    • G translation elongation factor mitochondrial antibody
    • GFM 1 antibody
    • GFM antibody
    • gfm1 antibody
    • hEFG1 antibody
    • mEF G 1 antibody
    • mEF-G 1 antibody
    • mEFG 1 antibody
    • mitochondrial antibody
    • Mitochondrial elongation factor G1 antibody
    see all

Anti-GFM1 antibody 画像

  • Anti-GFM1 antibody (ab107496) at 1/100 dilution + NCI-H460 cell line lysates at 35 µg

    Predicted band size : 83 kDa
  • Anti-GFM1 antibody (ab107496) at 1/100 dilution + Mouse heart tissue lysates at 35 µg

    Predicted band size : 83 kDa
  • ab107496, at a 1/50 dilution, staining GFM1 in formalin fixed and paraffin embedded Human bladder carcinoma, followed by peroxidase conjugation of the secondary antibody and DAB staining.

Anti-GFM1 antibody (ab107496) 使用論文

ab107496 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"