製品の概要

  • 製品名Anti-GERP antibody
    GERP 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to GERP
  • アプリケーション適用あり: IHC-P, ELISA, WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Chicken, Cow, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide within residues: RGCIGEAWAK DSGLVRCPEC NQAYNQKPGL EKNLKLTNIV EKFNALHVEK , corresponding to N terminal amino acids 35-84 of Human GERP (NP_112174)

  • ポジティブ・コントロール
    • HeLa cell lysate

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab83395 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use a concentration of 5 µg/ml.
ELISA Use at an assay dependent concentration.

ELISA titre using peptide based assay: 1/62500.

WB Use a concentration of 1 µg/ml. Detects a band of approximately 61 kDa (predicted molecular weight: 61 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Probable E3 ubiquitin-protein ligase which may promote proteasomal degradation of SOCS1.
  • 組織特異性Widely expressed.
  • パスウェイProtein modification; protein ubiquitination.
  • 配列類似性Belongs to the TRIM/RBCC family.
    Contains 2 B box-type zinc fingers.
    Contains 1 RING-type zinc finger.
  • ドメインThe coiled coil domain is required for homodimerization.
    The region immediately C-terminal to the RING motif is sufficient to mediate the interaction with SOCS1.
  • Information by UniProt
  • 参照データベース
  • 別名
    • AA408830 antibody
    • BB006755 antibody
    • Glioblastoma-expressed RING finger protein antibody
    • Lioblastoma expressed ring finger protein antibody
    • Probable E3 ubiquitin-protein ligase TRIM8 antibody
    • RING finger protein 27 antibody
    • RNF27 antibody
    • RP11-47A8.4 antibody
    • TRIM8 antibody
    • TRIM8_HUMAN antibody
    • Tripartite motif containing 8 antibody
    • Tripartite motif protein TRIM8 antibody
    • Tripartite motif-containing protein 8 antibody
    see all

Anti-GERP antibody 画像

  • Anti-GERP antibody (ab83395) at 1 µg/ml + HeLa cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 61 kDa
    Observed band size : 61 kDa
    Additional bands at : 25 kDa. We are unsure as to the identity of these extra bands.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human testis tissue labelling GERP with ab83395 at 5.0µg/ml.

Anti-GERP antibody (ab83395) 使用論文

ab83395 has not yet been referenced specifically in any publications.

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