Anti-Germinal Center Kinase 抗体 (ab38289)

製品の概要

  • 製品名Anti-Germinal Center Kinase antibody
    Germinal Center Kinase 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Germinal Center Kinase
  • アプリケーション適用あり: WB, IHC-P, ELISAmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide (10-30 aa in length) in the region of 302-318 (ELETYDMFPDTIHSRGQ) of human Human Germinal Center Kinase.

  • ポジティブ・コントロール
    • Mouse skeletal muscle tissue lysate. human hepatocarcinoma
  • 特記事項


    This antibody targets the center part of the protein.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab38289 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Detects a band of approximately 91 kDa (predicted molecular weight: 91 kDa).
IHC-P 1/50 - 1/100.
ELISA 1/1000.

ターゲット情報

  • 機能Enhances MAP3K1 oligomerization, which may relieve amino-terminal mediated MAP3K1 autoinhibition and lead to activation following autophosphorylation. May play a role in the regulation of vesicle targeting or fusion.
  • 組織特異性Highly expressed in germinal center but not mantle zone B-cells. Also expressed in lung, brain and placenta and at lower levels in other tissues examined.
  • 配列類似性Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
    Contains 1 CNH domain.
    Contains 1 protein kinase domain.
  • 細胞内局在Cytoplasm. Basolateral cell membrane. Golgi apparatus membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • B lymphocyte serine/threonine protein kinase antibody
    • B lymphocyte serine/threonine-protein kinase antibody
    • BL44 antibody
    • GC kinase antibody
    • GCK antibody
    • Germinal center kinase antibody
    • germinal centre kinase (GC kinase) antibody
    • M4K2_HUMAN antibody
    • Map4k2 antibody
    • MAPK/ERK kinase kinase kinase 2 antibody
    • MEK kinase kinase 2 antibody
    • MEKKK 2 antibody
    • Mitogen activated protein kinase kinase kinase kinase 2 antibody
    • Mitogen-activated protein kinase kinase kinase kinase 2 antibody
    • Rab8 interacting protein antibody
    • Rab8 interacting protein, formerly antibody
    • Rab8-interacting protein antibody
    • RAB8IP antibody
    • RAB8IP, formerly antibody
    see all

Anti-Germinal Center Kinase antibody 画像

  • Anti-Germinal Center Kinase antibody (ab38289) at 1/100 dilution + Mouse skeletal muscle tissue lysate.

    Predicted band size : 91 kDa
    Observed band size : 91 kDa
    Additional bands at : 45 kDa (possible degradation product).
  • 1/50 ab38289 staining human cancer tissue (hepatocarcinoma) by immunohistochemistry - formalin-fixed, paraffin-embedded tissue. The tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.

Anti-Germinal Center Kinase antibody (ab38289) 使用論文

ab38289 has not yet been referenced specifically in any publications.

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