Anti-GDF15 抗体 (ab105738)
Key features and details
- Rabbit polyclonal to GDF15
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG
製品の概要
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製品名
Anti-GDF15 antibody
GDF15 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to GDF15 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Mouse, Human
交差が予測される動物種: Rat, Cow, Dog, Pig -
免疫原
Synthetic peptide corresponding to amino acids near the C-terminal of Mouse GDF15.
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特記事項
Expiration date is one (1) year from date of opening product.The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
Preservative: 0.01% Sodium azide
Constituents: 0.42% Potassium phosphate, 0.88% Sodium chloride -
Concentration information loading...
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精製度
Protein A purified -
特記事項(精製)
ab105738 is affinity purified from monospecific antiserum by immunoaffinity chromatography. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab105738の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/3000 - 1/7000. Predicted molecular weight: 33 kDa.
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特記事項 |
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WB
1/3000 - 1/7000. Predicted molecular weight: 33 kDa. |
ターゲット情報
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組織特異性
Highly expressed in placenta, with lower levels in prostate and colon and some expression in kidney. -
配列類似性
Belongs to the TGF-beta family. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 618677 Cow
- Entrez Gene: 9518 Human
- Entrez Gene: 23886 Mouse
- Entrez Gene: 29455 Rat
- Omim: 605312 Human
- SwissProt: Q99988 Human
- SwissProt: Q9Z0J7 Mouse
- SwissProt: Q9Z0J6 Rat
see all -
別名
- GDF 15 antibody
- GDF-15 antibody
- Gdf15 antibody
see all
画像
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All lanes : Anti-GDF15 antibody (ab105738) at 1/1000 dilution
Lane 1 : Recombinant MBP-GDF15 fusion protein purified from E.coli
Lane 2 : Yeast cell lysate expressing SUMO-Mouse GDF15
Lane 3 : Human GDF15 monomer purified from CHO-K1 cells
Secondary
All lanes : Goat-anti-Rabbit HRP at 1/40000 dilution
Performed under reducing conditions.
Predicted band size: 33 kDa
Expect bands in Western blots of approximately 14 and 28 kDa in size corresponding to GDF15 monomer and dimer, respectively.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab105738 は 2 報の論文で使用されています。
- Patsalos A et al. A growth factor-expressing macrophage subpopulation orchestrates regenerative inflammation via GDF-15. J Exp Med 219:N/A (2022). PubMed: 34846534
- Weng JH et al. Colchicine acts selectively in the liver to induce hepatokines that inhibit myeloid cell activation. Nat Metab 3:513-522 (2021). PubMed: 33846641