製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to GDF 9
  • 特異性
    This antibody is specific for GDF 9 (N term).
  • アプリケーション
    適用あり: ELISA, IHC-P, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    A KLH conjugated synthetic peptide (10-30 aa in length) at the N-term of first 60 aa of human GDF 9.

  • ポジティブ・コントロール
    • HL60 cell lysate and hepatocarcinoma tissue.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • バッファー
    Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 精製度
    Protein G purified
  • 特記事項(精製)
    This antibody is purified through a protein G column and eluted out with both high and low pH buffers and neutralized immediately after elution then followed by dialysis against PBS.
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab38544 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/1000.
IHC-P 1/50 - 1/100.
WB 1/100 - 1/500. Detects a band of approximately 51 kDa (predicted molecular weight: 51 kDa).

ターゲット情報

  • 関連性
    GDF 9 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Growth factors synthesized by ovarian somatic cells directly affect oocyte growth and function. GDF 9 is expressed in oocytes and is thought to be required for ovarian folliculogenesis.
  • 細胞内局在
    Secreted
  • 参照データベース
  • 別名
    • GDF9 antibody
    • Growth differentiation factor 9 antibody

Anti-GDF 9 antibody 画像

  • Anti-GDF 9 antibody (ab38544) at 1/100 dilution + HL60 cell lysate

    Predicted band size : 51 kDa
    Observed band size : 51 kDa
  • Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ab38544 at a 1/50 dilution, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.

    This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-GDF 9 antibody (ab38544) 使用論文

This product has been referenced in:
  • Hu X  et al. Stem cells derived from human first-trimester umbilical cord have the potential to differentiate into oocyte-like cells in vitro. Int J Mol Med 35:1219-29 (2015). Read more (PubMed: 25760093) »
  • Wang Y  et al. Extra-ovarian expression and activity of growth differentiation factor 9. J Endocrinol 202:419-30 (2009). Read more (PubMed: 19505950) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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