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RabMAb

Anti-GCN2 (phospho T667) 抗体 [EPR2319Y] (ab68427)

製品の概要

  • 製品名
    Anti-GCN2 (phospho T667) antibody [EPR2319Y]
    GCN2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EPR2319Y] to GCN2 (phospho T667)
  • 特異性
    Detects GCN2 only when phosphorylyated at threonine 667.
  • アプリケーション
    適用あり: WB, IPmore details
    適用なし: Flow Cyt,ICC/IF or IHC-P
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic phosphopeptide corresponding to residues surrounding threonine 667 of human GCN2.

  • ポジティブ・コントロール
    • HeLa cells
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab68427 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000 - 1/2000. Detects a band of approximately 220 kDa (predicted molecular weight: 220 kDa).
IP 1/30.
  • 追加情報
    Is unsuitable for Flow Cyt,ICC/IF or IHC-P.
  • ターゲット情報

    • 機能
      Can phosphorylate the alpha subunit of EIF2 and may mediate translational control.
    • 組織特異性
      Widely expressed.
    • 配列類似性
      Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.
      Contains 2 protein kinase domains.
      Contains 1 RWD domain.
    • ドメイン
      Kinase domain 1 is a degenerate kinase domain.
      RWD domain is reported to interact with GCN1L1.
    • 翻訳後修飾
      Autophosphorylated on threonine residues.
    • Information by UniProt
    • 参照データベース
    • 別名
      • E2AK4_HUMAN antibody
      • Eif2ak4 antibody
      • Eukaryotic Translation Initiation Factor 2 alpha kinase 4 antibody
      • Eukaryotic translation initiation factor 2-alpha kinase 4 antibody
      • GCN2 antibody
      • GCN2 eIF2alpha kinase antibody
      • GCN2 like protein antibody
      • GCN2-like protein antibody
      • KIAA1338 antibody
      • MGCN2 antibody
      see all

    画像

    • All lanes : Anti-GCN2 (phospho T667) antibody [EPR2319Y] (ab68427) at 1/2000 dilution

      Lane 1 : HeLa cell lysate - untreated
      Lane 2 : HeLa cell lysate - treated with LP

      Lysates/proteins at 10 µg per lane.

      Secondary
      HRP labelled Goat anti-Rabbit antibody at 1/2000 dilution

      Predicted band size : 220 kDa
      Observed band size : 220 kDa
      Additional bands at : 180 kDa. We are unsure as to the identity of these extra bands.

    参考文献

    ab68427 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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