Anti-GCN2 (phospho T667) 抗体 [EPR2319Y] (ab68427)

製品の概要

  • 製品名Anti-GCN2 (phospho T667) antibody [EPR2319Y]
    GCN2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EPR2319Y] to GCN2 (phospho T667)
  • 特異性Detects GCN2 only when phosphorylyated at threonine 667.
  • アプリケーション適用あり: WB, IPmore details
    適用なし: Flow Cyt,ICC/IF or IHC-P
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic phosphopeptide corresponding to residues surrounding threonine 667 of human GCN2.

  • ポジティブ・コントロール
    • HeLa cells
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab68427 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000 - 1/2000. Detects a band of approximately 220 kDa (predicted molecular weight: 220 kDa).
IP 1/30.
  • 追加情報Is unsuitable for Flow Cyt,ICC/IF or IHC-P.
  • ターゲット情報

    • 機能Can phosphorylate the alpha subunit of EIF2 and may mediate translational control.
    • 組織特異性Widely expressed.
    • 配列類似性Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.
      Contains 2 protein kinase domains.
      Contains 1 RWD domain.
    • ドメインKinase domain 1 is a degenerate kinase domain.
      RWD domain is reported to interact with GCN1L1.
    • 翻訳後修飾Autophosphorylated on threonine residues.
    • Information by UniProt
    • 参照データベース
    • 別名
      • E2AK4_HUMAN antibody
      • Eif2ak4 antibody
      • Eukaryotic Translation Initiation Factor 2 alpha kinase 4 antibody
      • Eukaryotic translation initiation factor 2-alpha kinase 4 antibody
      • GCN2 antibody
      • GCN2 eIF2alpha kinase antibody
      • GCN2 like protein antibody
      • GCN2-like protein antibody
      • KIAA1338 antibody
      • MGCN2 antibody
      see all

    Anti-GCN2 (phospho T667) antibody [EPR2319Y] 画像

    • All lanes : Anti-GCN2 (phospho T667) antibody [EPR2319Y] (ab68427) at 1/2000 dilution

      Lane 1 : HeLa cell lysate - untreated
      Lane 2 : HeLa cell lysate - treated with LP

      Lysates/proteins at 10 µg per lane.

      Secondary
      HRP labelled Goat anti-Rabbit antibody at 1/2000 dilution

      Predicted band size : 220 kDa
      Observed band size : 220 kDa
      Additional bands at : 180 kDa. We are unsure as to the identity of these extra bands.

    Anti-GCN2 (phospho T667) antibody [EPR2319Y] (ab68427) 使用論文

    ab68427 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"