製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to GCAT
  • アプリケーション
    適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Synthetic peptide conjugated to KLH, from the internal region of Human GCAT.

  • ポジティブ・コントロール
    • Mouse liver tissue lysates.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab85202 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/50 - 1/100. Detects a band of approximately 45 kDa (predicted molecular weight: 45 kDa).
ELISA 1/1000.

ターゲット情報

  • 組織特異性
    Strongly expressed in heart, brain, liver and pancreas. Also found in lung.
  • パスウェイ
    Amino-acid degradation; L-threonine degradation via oxydo-reductase pathway; glycine from L-threonine: step 2/2.
  • 配列類似性
    Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
  • 細胞内局在
    Mitochondrion.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 2 amino 3 ketobutyrate CoA ligase antibody
    • 2 amino 3 ketobutyrate coenzyme A ligase, mitochondrial antibody
    • 2-amino-3-ketobutyrate coenzyme A ligase antibody
    • AKB ligase antibody
    • Aminoacetone synthase antibody
    • GCAT antibody
    • Glycine acetyltransferase antibody
    • glycine C acetyltransferase antibody
    • glycine C acetyltransferase (2 amino 3 ketobutyrate coenzyme A ligase) antibody
    • KBL_HUMAN antibody
    • KLB antibody
    • mitochondrial antibody
    see all

画像

  • Anti-GCAT antibody (ab85202) at 1/50 dilution + Mouse liver tissue lysates at 35 µg

    Predicted band size : 45 kDa
    Observed band size : 45 kDa
    Additional bands at : 32 kDa,65 kDa. We are unsure as to the identity of these extra bands.

プロトコール

参考文献

This product has been referenced in:
  • Kim D  et al. SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance. Nature 520:363-7 (2015). Read more (PubMed: 25855294) »

See 1 Publication for this product

レビューと Q&A

There are currently no Customer reviews or Questions for ab85202.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録