The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
追加情報WB: 1/500 - 1/1000. Detects a band of approximately 15 kDa (predicted molecular weight for isoform 2: 18 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
機能Glycosidase probably involved in the intestinal absorption and metabolism of dietary flavonoid glycosides. Able to hydrolyze a broad variety of glycosides including phytoestrogens, flavonols, flavones, flavanones and cyanogens. Possesses beta-glycosylceramidase activity and may be involved in a nonlysosomal catabolic pathway of glycosylceramide.
組織特異性Present in small intestine (at protein level). Expressed in liver, small intestine, colon, spleen and kidney. Down-regulated in renal cell carcinomas and hepatocellular carcinomas.
配列類似性Belongs to the glycosyl hydrolase 1 family. Klotho subfamily.