製品の概要

  • 製品名Anti-Gasdermin like antibody
    Gasdermin like 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to Gasdermin like
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-412 of Human Gasdermin like

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • アイソタイプIgG2b
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab57438 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能The N-terminal moiety promotes pyroptosis. May be acting by homooligomerizing within the membrane and forming pores (PubMed:27281216). The physiological relevance of this observation is unknown.
    • 組織特異性In the gastrointestinal tract, expressed in proliferating cells, including in the basal cell layer of esophagus and in isthmus/neck of stomach.
    • 配列類似性Belongs to the gasdermin family.
    • ドメインIntramolecular interactions between N- and C-terminal domains may be important for autoinhibition in the absence of activation signal. The intrinsic pyroptosis-inducing activity is carried by the N-terminal domain.
    • 細胞内局在Cytoplasm. Cytoplasm, cytosol. Cell membrane. Vesicular localization in the apical region of gastric chief cells and colonic surface mucous cells, and the basal region of neuroendocrine cells.
    • Information by UniProt
    • 参照データベース
    • 製品の状態There are 5 isoforms produced by alternative splicing.
    • 別名
      • 123 antibody
      • 156 antibody
      • Gasdermin B antibody
      • Gasdermin like protein antibody
      • Gasdermin-B antibody
      • Gasdermin-like protein antibody
      • GSDMB antibody
      • GSDMB_HUMAN antibody
      • GSDML antibody
      • PP4052 antibody
      • PRO2521 antibody
      see all

    Anti-Gasdermin like antibody 画像



    • Predicted band size : 47 kDa
      Gasdermin like antibody (ab57438) at 1ug/lane + Jurkat cell lysate at 25ug/lane.

    Anti-Gasdermin like antibody (ab57438) 使用論文

    ab57438 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab57438.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"