製品の概要

  • 製品名
    Anti-GAP43 antibody [EP928Y]
    GAP43 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EP928Y] to GAP43
  • 特異性
    ab75843 detects both phosphorylated and nonphosphorylated GAP43.
  • アプリケーション
    適用あり: WB, ICCmore details
    適用なし: Flow Cyt,IHC-P or IP
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    A synthetic peptide corresponding to residues surrounding serine 41 of human GAP43

  • ポジティブ・コントロール
    • Human brain lysate.
  • 特記事項

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab75843 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/50000 - 1/100000. Detects a band of approximately 48 kDa (predicted molecular weight: 25 kDa).
ICC 1/100 - 1/250.
  • 追加情報
    Is unsuitable for Flow Cyt,IHC-P or IP.
  • ターゲット情報

    • 機能
      This protein is associated with nerve growth. It is a major component of the motile "growth cones" that form the tips of elongating axons.
    • 配列類似性
      Belongs to the neuromodulin family.
      Contains 1 IQ domain.
    • 翻訳後修飾
      Phosphorylation of this protein by a protein kinase C is specifically correlated with certain forms of synaptic plasticity.
    • 細胞内局在
      Cell membrane. Cell projection > growth cone membrane. Cell junction > synapse. Cytoplasmic surface of growth cone and synaptic plasma membranes.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Axonal membrane protein GAP 43 antibody
      • Axonal membrane protein GAP-43 antibody
      • B 50 antibody
      • Calmodulin binding protein P 57 antibody
      • F1 antibody
      • GAP 43 antibody
      • GAP43 antibody
      • Growth Associated Protein 43 antibody
      • Growth-associated protein 43 antibody
      • Nerve Growth Related Peptide antibody
      • Nerve growth related peptide GAP43 antibody
      • NEUM_HUMAN antibody
      • Neural phosphoprotein B 50 antibody
      • Neural phosphoprotein B-50 antibody
      • Neuromodulin antibody
      • Neuron growth associated protein 43 antibody
      • PP46 antibody
      • Protein F1 antibody
      • QtrA-11580 antibody
      • QtrA-13071 antibody
      see all

    画像

    • Anti-GAP43 antibody [EP928Y] (ab75843) at 1/100000 dilution + human brain lysate at 10 µg

      Secondary
      HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size : 25 kDa
      Observed band size : 48 kDa (why is the actual band size different from the predicted?)

    参考文献

    This product has been referenced in:
    • Zhang G  et al. Combined application of Rho-ROCKII and GSK-3ß inhibitors exerts an improved protective effect on axonal regeneration in rats with spinal cord injury. Mol Med Rep 14:5180-5188 (2016). Read more (PubMed: 27840930) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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