The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Thin Layer Chromatography
ELISA: 1/10 - 1/100.
TLC: Use at an assay dependent dilution.
WB: 1/5 - 1/50.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Gangliosides are a group of galactose-containing cerebrosides found in the surface membranes of nerve cells.
Ganglioside GD2 is a disialoganglioside expressed on tumors of neuroectodermal origin, including human neuroblastoma and melanoma, with highly restricted expression on normal tissues, principally to the cerebellum and peripheral nerves in humans. GD2 is a suitable target for immunotherapy with monoclonal antibodies or with artificial T cell receptors due to its relatively tumor specific expression.