Anti-Ganglioside asialo GM2 抗体 (ab23942)

製品の概要

  • 製品名
    Anti-Ganglioside asialo GM2 antibody
  • 製品の詳細
    Rabbit polyclonal to Ganglioside asialo GM2
  • 特異性
    No cross-reaction with other carbohydrate epitopes.
  • アプリケーション
    適用あり: WB, ELISA, Thin Layer Chromatographymore details
  • 種交差性
    Reacts with a wide range of species.
  • 免疫原

    Purified ganglioside asialo GM2 and complete Freunds adjuvant (Human).

  • 特記事項


    This product is a mix of IgG and IgM.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファー
    Preservative: None
    Constituents: Whole serum
  • 精製度
    Whole antiserum
  • 一次抗体 備考
    This product is a mix of IgG and IgM.
  • ポリ/モノ
    ポリクローナル
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab23942 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use at an assay dependent concentration. Predicted molecular weight: 1 kDa.
ELISA 1/1600.
Thin Layer Chromatography 1/100.

Phosphate buffered saline (pH 7.4) is the recommended diluent.

ターゲット情報

  • 関連性
    Ganglioside is a compound composed of lipid and carbohydrate (glycosphingolipids) that is produced as a component of the plasma membrane of many kinds of cells. It is a component of cells found in nerve tissue endings and function in nerve impulse transmission. If these are not degenerated by enzymes, they can build up and cause brain and nerve cell damage.
  • 細胞内局在
    Plasma membrane and Secreted
  • 別名
    • Asialo GM 2 antibody
    • Asialo GM 2 ganglioside antibody
    • Asialo GM2 antibody
    • Asialo GM2 ganglioside antibody
    • Ganglioside asialo GM 2 antibody
    see all

プロトコール

Anti-Ganglioside asialo GM2 antibody (ab23942) 使用論文

This product has been referenced in:
  • Alvarez AR  et al. Imatinib therapy blocks cerebellar apoptosis and improves neurological symptoms in a mouse model of Niemann-Pick type C disease. FASEB J : (2008). Read more (PubMed: 18591368) »

See 1 Publication for this product

Product Wall

Application
Immunohistochemistry (Frozen sections)
Sample
Mouse Tissue sections (Brain and Liver)
Permeabilization
Yes - Hydrogen peroxide-10min
Specification
Brain and Liver
Blocking step
ab64260 protein block reagent as blocking agent for 10 minute(s) · Concentration: 5% · Temperature: RT°C
Fixative
Paraformaldehyde
Username

Abcam user community

Verified customer

投稿 Sep 19 2016

Thank you for your recent telephone enquiry.

I have now received in formation to confirm thatthe anti-asialo GM2 antibody ab23942 does not react with monosialo-GM2.

I am sorry this is not better news for you and this product would...

Read More

I'm afraid we were unable to reach the laboratory that tested the antibody ab23942 to find out what tissues were used. However, I believe that Ganglioside asialo GM2 is a compound that is conserved in all species, of sequence GgOse3Cer; ß-GalNAc-(1?4)...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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