製品の概要

  • 製品名Anti-gamma Synuclein antibody
    gamma Synuclein 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to gamma Synuclein
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 100 to the C-terminus of Human gamma Synuclein.

    (Peptide available as ab46713.)

  • ポジティブ・コントロール
    • This antibody gave a positive signal in Gamma Synuclein recombinant protein.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab46201 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 0.5 µg/ml. Detects a band of approximately 15 kDa corresponding to the molecular weight of the full length Gamma Synuclein recombinant protein.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity). May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway.
    • 組織特異性Highly expressed in brain, particularly in the substantia nigra. Also expressed in the corpus callosum, heart, skeletal muscle, ovary, testis, colon and spleen. Weak expression in pancreas, kidney and lung.
    • 配列類似性Belongs to the synuclein family.
    • 翻訳後修飾Phosphorylated. Phosphorylation by GRK5 appears to occur on residues distinct from the residue phosphorylated by other kinases.
    • 細胞内局在Cytoplasm > perinuclear region. Cytoplasm > cytoskeleton > centrosome. Cytoplasm > cytoskeleton > spindle. Associated with centrosomes in several interphase cells. In mitotic cells, localized to the poles of the spindle.
    • Information by UniProt
    • 参照データベース
    • 別名
      • BCSG1 antibody
      • Breast cancer specific gene 1 protein antibody
      • Breast cancer specific protein 1 antibody
      • Breast cancer-specific gene 1 protein antibody
      • Gamma synuclein antibody
      • Gamma-synuclein antibody
      • Persyn antibody
      • PRSN antibody
      • SNCG antibody
      • SR antibody
      • Synoretin antibody
      • Synuclein gamma antibody
      • synuclein, gamma (breast cancer-specific protein 1) antibody
      • SYUG_HUMAN antibody
      see all

    Anti-gamma Synuclein antibody 画像

    • Anti-gamma Synuclein antibody (ab46201) at 0.5 µg/ml + Recombinant Human gamma Synuclein protein (ab48712) at 0.05 µg

      Secondary
      Goat polyclonal to rabbit IgG - H&L - Pre adsorbed (HRP) at 1/3000 dilution

      Performed under reducing conditions.

      Observed band size : 15 kDa (why is the actual band size different from the predicted?)

    Anti-gamma Synuclein antibody (ab46201) 使用論文

    ab46201 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab46201.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"