Anti-gamma Sarcoglycan 抗体 (ab104478)
Key features and details
- Rabbit polyclonal to gamma Sarcoglycan
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-gamma Sarcoglycan antibody
gamma Sarcoglycan 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to gamma Sarcoglycan -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Recombinant full length protein within Human gamma Sarcoglycan. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Constituent: 100% PBS -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab104478の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 32 kDa.
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特記事項 |
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WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 32 kDa. |
ターゲット情報
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機能
Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. -
組織特異性
Expressed in skeletal and heart muscle. -
関連疾患
Defects in SGCG are the cause of limb-girdle muscular dystrophy type 2C (LGMD2C) [MIM:253700]. LGMD2C is characterized by progressive muscle wasting from early childhood. -
配列類似性
Belongs to the sarcoglycan beta/delta/gamma/zeta family. -
細胞内局在
Cell membrane > sarcolemma. Cytoplasm > cytoskeleton. - Information by UniProt
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参照データベース
- Entrez Gene: 6445 Human
- Omim: 608896 Human
- SwissProt: Q13326 Human
- Unigene: 37167 Human
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別名
- 35 kDa dystrophin associated glycoprotein antibody
- 35 kDa dystrophin-associated glycoprotein antibody
- 35DAG antibody
see all
画像
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Anti-gamma Sarcoglycan antibody (ab104478) at 1 µg/ml + Human kidney tissue lysate at 50 µg
Predicted band size: 32 kDa -
All lanes : Anti-gamma Sarcoglycan antibody (ab104478) at 1 µg/ml
Lane 1 : gamma Sarcoglycan transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 25 µg per lane.
Predicted band size: 32 kDa
データシートおよび資料
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Datasheet download
参考文献 (1)
ab104478 は 1 報の論文で使用されています。
- van den Bergen JC et al. Clinical characterisation of Becker muscular dystrophy patients predicts favourable outcome in exon-skipping therapy. J Neurol Neurosurg Psychiatry N/A:N/A (2013). Human . PubMed: 23667215