製品の概要

  • 製品名
    Anti-gamma C Crystallin antibody
  • 製品の詳細
    Rabbit polyclonal to gamma C Crystallin
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Rabbit, Horse, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within the internal amino acids 72-121 (LSDSIRSCCL IPQTVSHRLR LYEREDHKGL MMELSEDCPS IQDRFHLSEI) of Human gamma C Crystallin (NP_066269).

  • ポジティブ・コントロール
    • OVCAR-3 cell lysate

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファー
    Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab90333 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 21 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能
    Crystallins are the dominant structural components of the vertebrate eye lens.
  • 関連疾患
    Defects in CRYGC are a cause of cataract autosomal dominant (ADC) [MIM:604219]. Cataract is an opacification of the crystalline lens of the eye that frequently results in visual impairment or blindness. Opacities vary in morphology, are often confined to a portion of the lens, and may be static or progressive. In general, the more posteriorly located and dense an opacity, the greater the impact on visual function. Cataract is the most common treatable cause of visual disability in childhood.
    Defects in CRYGC are a cause of cataract Coppock-like (CCL) [MIM:604307]. A congenital pulverulent disk-like opacity involving the embryonic nucleus with many tiny white dots in the lamellar portion of the lens. It is usually bilateral and dominantly inherited.
  • 配列類似性
    Belongs to the beta/gamma-crystallin family.
    Contains 4 beta/gamma crystallin 'Greek key' domains.
  • ドメイン
    Has a two-domain beta-structure, folded into four very similar Greek key motifs.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CATARACT, VARIABLE ZONULAR PULVERULENT antibody
    • CCL antibody
    • CRGC_HUMAN antibody
    • CRYG 3 antibody
    • Cryg 5 antibody
    • Cryg antibody
    • CRYG3 antibody
    • CRYGC antibody
    • Crystallin gamma 3 antibody
    • Crystallin gamma C antibody
    • Gamma C crystallin antibody
    • Gamma crystallin 2 1 antibody
    • Gamma crystallin 3 antibody
    • Gamma crystallin C antibody
    • Gamma-C-crystallin antibody
    • Gamma-crystallin 2-1 antibody
    • Gamma-crystallin 3 antibody
    • Gamma-crystallin C antibody
    • Gammab cry antibody
    • Len antibody
    see all

画像

  • Anti-gamma C Crystallin antibody (ab90333) at 1 µg/ml (in 5% skim milk / PBS buffer) + OVCAR-3 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 21 kDa

プロトコール

参考文献

ab90333 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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