製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to GALNTL6
  • アプリケーション
    適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    antigen sequence corresponding to amino acids 33-114 (DKHLVKSAEP GEQQTFPLGL GDGQFYSWTD GLRRKDWHDY ESIQKEAMRS GKGEHGKPYP LTEEDHDDSA YRENGFNIFV SN) of Human GALNTL6.

  • ポジティブ・コントロール
    • Human Placenta tissue; RT-4 and U-251 MG cell lysate.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファー
    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab122149 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/250 - 1/500.
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能
    Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor.
  • パスウェイ
    Protein modification; protein glycosylation.
  • 配列類似性
    Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
    Contains 1 ricin B-type lectin domain.
  • ドメイン
    There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding.
    The ricin B-type lectin domain binds to GalNAc and contributes to the glycopeptide specificity.
  • 細胞内局在
    Golgi apparatus membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • EC 2.4.1.41 antibody
    • GalNAc transferase 17 antibody
    • GalNAc-T17 antibody
    • GALNACT20 antibody
    • GALNTL6 antibody
    • GaNTase 17 antibody
    • GLTL6_HUMAN antibody
    • MGC44629 antibody
    • OTTHUMP00000219021 antibody
    • OTTHUMP00000219023 antibody
    • Polypeptide GalNAc transferase 17 antibody
    • Polypeptide N-acetylgalactosaminyltransferase-like 6 antibody
    • polypeptide N-acetylgalactosaminyltransferase-like 6 UDP-N-acetyl-alpha-D-galactosamine:polypeptideN-acetylgalactosaminyltransferase 20 antibody
    • pp-GaNTase 17 antibody
    • Protein-UDP acetylgalactosaminyltransferase 17 antibody
    • Putative polypeptide N-acetylgalactosaminyltransferase 17 antibody
    • UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 17 antibody
    • UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like antibody
    see all

画像

  • All lanes : Anti-GALNTL6 antibody (ab122149) at 1/250 dilution

    Lane 1 : RT-4 cell lysate
    Lane 2 : U-251 MG cell lysate
    Lane 3 : Human Plasma
    Lane 4 : Human Liver lysate
    Lane 5 : Human Tonsil lysate

    Developed using the ECL technique
  • ab122149, at 1/135, staining GALNTL6 in paraffin-embedded Human placenta tissue by Immunohistochemistry.

参考文献

ab122149 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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