製品の概要

  • 製品名Anti-GALNT11 antibody
    GALNT11 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to GALNT11
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Rat
    交差が予測される動物種: Mouse, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within N-terminal amino acids 98-147 (LGMIFNERDQ ELRDLGYQKH AFNMLISNRL GYHRDVPDTR NAECRRKSYP) of Rat GALNT11 (NP_955425).

  • ポジティブ・コントロール
    • Rat heart lysate.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファーConstituents: PBS, 2% Sucrose
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab110861 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 69 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Displays the same enzyme activity toward Muc1, Muc4.1, and EA2 than GALNT1. Does not appear to be involved in glycosylation of erythropoietin.
  • 組織特異性Highly expressed in kidney. Expressed at intermediate level in brain, heart and skeletal muscle. Weakly expressed other tissues. In kidney, it is strongly expressed in tubules but not expressed in glomeruli.
  • パスウェイProtein modification; protein glycosylation.
  • 配列類似性Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
    Contains 1 ricin B-type lectin domain.
  • ドメインThere are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding.
    The ricin B-type lectin domain binds to GalNAc and contributes to the glycopeptide specificity.
  • 細胞内局在Golgi apparatus membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • A430075I06Rik antibody
    • AI648252 antibody
    • E430002F06Rik antibody
    • FLJ21634 antibody
    • GalNAc Transferase 11 antibody
    • GalNAc-T11 antibody
    • GalNAcT11 antibody
    • GALNT11 antibody
    • GLT11_HUMAN antibody
    • MGC71630 antibody
    • Polypeptide GalNAc transferase 11 antibody
    • Polypeptide N-acetylgalactosaminyltransferase 11 antibody
    • pp-GaNTase 11 antibody
    • Protein-UDP acetylgalactosaminyltransferase 11 antibody
    • tcag7.1057 antibody
    • UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 11 antibody
    • UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11) antibody
    see all

Anti-GALNT11 antibody 画像

  • Anti-GALNT11 antibody (ab110861) at 1 µg/ml + Rat heart lysate at 10 µg

    Predicted band size : 69 kDa

Anti-GALNT11 antibody (ab110861) 使用論文

ab110861 has not yet been referenced specifically in any publications.

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