製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to GALNT10
  • アプリケーション
    適用あり: ICC/IF, WB, IHC-Pmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    An 18 amino acid synthetic peptide near the C terminus of Human GALNT10 (NP_938080).

  • ポジティブ・コントロール
    • SK-N-SH cell lysate; Human brain tissue

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at 4°C (stable for up to 12 months).
  • バッファー
    Preservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab106471 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 69 kDa.
IHC-P Use a concentration of 2.5 µg/ml.

ターゲット情報

  • 機能
    Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward Muc5Ac and EA2 peptide substrates.
  • 組織特異性
    Widely expressed. Expressed at high level in small intestine, and at intermediate levels in stomach, pancreas, ovary, thyroid gland and spleen. Weakly expressed in other tissues.
  • パスウェイ
    Protein modification; protein glycosylation.
  • 配列類似性
    Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
    Contains 1 ricin B-type lectin domain.
  • ドメイン
    There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding.
    The ricin B-type lectin domain binds to GalNAc and contributes to the glycopeptide specificity.
  • 細胞内局在
    Golgi apparatus membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • DKFZp586H0623 antibody
    • FLJ00205 antibody
    • FLJ11715 antibody
    • GalNAc T10 antibody
    • GalNAc transferase 10 antibody
    • GalNAc-T10 antibody
    • GalNAcT10 antibody
    • GALNT10 antibody
    • GLT10_HUMAN antibody
    • Polypeptide GalNAc transferase 10 antibody
    • Polypeptide N-acetylgalactosaminyltransferase 10 antibody
    • pp GalNAc T10 antibody
    • pp GaNTase 10 antibody
    • pp-GaNTase 10 antibody
    • ppGalNAcT10 antibody
    • ppGaNTase 10 antibody
    • Protein UDP acetylgalactosaminyltransferase 10 antibody
    • Protein-UDP acetylgalactosaminyltransferase 10 antibody
    • UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 10 antibody
    • UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 10 antibody
    • UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10 antibody
    • UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10) antibody
    see all

画像

  • Lane 1 : Anti-GALNT10 antibody (ab106471) at 1 µg/ml
    Lane 2 : Anti-GALNT10 antibody (ab106471) at 2 µg/ml

    Lane 1 : SK-N-SH cell lysate
    Lane 2 : SK-N-SH cell lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 69 kDa
  • ab106471, at 2.5 µg/ml, staining GALNT10 in Human brain tissue by Immunohistochemistry.
  • Immunofluorescence of GALNT10 in Human Brain cells using ab106471 at 20 ug/ml.

参考文献

ab106471 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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