製品の概要

  • 製品名Anti-GALNT1 antibody
    GALNT1 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to GALNT1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length human GALNT1 protein (AAH47746.1)

  • ポジティブ・コントロール
    • GALNT1 transfected 293T cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab69959 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: 1/500 - 1/1000. Detects a band of <10 kDa (predicted molecular weight: Isoform 2, 12 kDa; Isoform 1, 64 kDa).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b and Muc7.
    • 組織特異性Widely expressed. Expressed in all tissues tested.
    • パスウェイProtein modification; protein glycosylation.
    • 配列類似性Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
      Contains 1 ricin B-type lectin domain.
    • ドメインThere are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding.
      The ricin B-type lectin domain directs the glycopeptide specificity. It is required in the glycopeptide specificity of enzyme activity but not for activity with naked peptide substrates, suggesting that it triggers the catalytic domain to act on GalNAc-glycopeptide substrates.
    • 細胞内局在Secreted and Golgi apparatus > Golgi stack membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • GALNAC T1 antibody
      • GalNAc transferase 1 antibody
      • GalNAc-T1 antibody
      • GALNT 1 antibody
      • GALNT1 antibody
      • GALT1_HUMAN antibody
      • Polypeptide GalNAc transferase 1 antibody
      • Polypeptide N acetylgalactosaminyltransferase 1 antibody
      • Polypeptide N-acetylgalactosaminyltransferase 1 soluble form antibody
      • pp GaNTase 1 antibody
      • pp-GaNTase 1 antibody
      • Protein UDP acetylgalactosaminyltransferase 1 antibody
      • Protein-UDP acetylgalactosaminyltransferase 1 antibody
      • UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 1 antibody
      • UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 1 (GalNAc T1) antibody
      • UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 1 antibody
      • UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1 antibody
      see all

    Anti-GALNT1 antibody 画像

    • All lanes : Anti-GALNT1 antibody (ab69959) at 1/500 dilution

      Lane 1 : GALNT1 transfected 293T cell lysate
      Lane 2 : Non-transfected 293T cell lysate

      Lysates/proteins at 25 µg per lane.

      Secondary
      Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

      Predicted band size : 12 kDa
      Observed band size : <10 kDa (why is the actual band size different from the predicted?)

    Anti-GALNT1 antibody (ab69959) 使用論文

    ab69959 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab69959.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"