The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1000 - 1/10000. Detects a band of approximately 15 kDa (predicted molecular weight: 15 kDa).
1/10 - 1/100.
1/500 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
1/100 - 1/250.
追加情報Is unsuitable for Flow Cyt.
機能Could be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control. Pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release.
組織特異性Mainly expressed in stratified squamous epithelium.
配列類似性Contains 1 galectin domain.
細胞内局在Cytoplasm. Nucleus. Secreted. May be secreted by a non-classical secretory pathway.
Guo JP & Li XG Galectin-7 promotes the invasiveness of human oral squamous cell carcinoma cells via activation of ERK and JNK signaling. Oncol Lett13:1919-1924 (2017).
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