製品の概要

  • 製品名Anti-GALE antibody [1C4]
    GALE 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [1C4] to GALE
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Rat, Dog, Human, Monkey
  • 免疫原

    Recombinant full length Human GALE produced in HEK293T cells (NP_000394).

  • ポジティブ・コントロール
    • HEK293T cell lysate transfected with the pCMV6-ENTRY GALE cDNA; HepG2, HeLa, HT29, A549, COS7, Jurkat, MDCK, PC12 and MCF7 cell lysates.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab118033 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/2000. Predicted molecular weight: 38 kDa.

ターゲット情報

  • 機能Catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine.
  • パスウェイCarbohydrate metabolism; galactose metabolism.
  • 関連疾患Defects in GALE are the cause of epimerase-deficiency galactosemia (EDG) [MIM:230350]; also known as galactosemia type 3. Clinical features include early-onset cataracts, liver damage, deafness and mental retardation. There are two clinically distinct forms of EDG. (1) A benign, or 'peripheral' form with no detectable GALE activity in red blood cells and characterized by mild symptoms. Some patients may suffer no symptoms beyond raised levels of galactose-1-phosphate in the blood. (2) A much rarer 'generalized' form with undetectable levels of GALE activity in all tissues and resulting in severe features such as restricted growth and mental development.
  • 配列類似性Belongs to the sugar epimerase family.
  • Information by UniProt
  • 参照データベース
  • 別名
    • FLJ95174 antibody
    • FLJ97302 antibody
    • Galactose 4 epimerase UDP antibody
    • Galactowaldenase antibody
    • galE antibody
    • GALE_HUMAN antibody
    • OTTHUMP00000002991 antibody
    • OTTHUMP00000002994 antibody
    • OTTHUMP00000037931 antibody
    • OTTHUMP00000044857 antibody
    • SDR1E1 antibody
    • short chain dehydrogenase/reductase family 1E member 1 antibody
    • UDP galactose 4 epimerase antibody
    • UDP galactose 4' epimerase antibody
    • UDP glucose 4 epimerase antibody
    • UDP-galactose 4-epimerase antibody
    • UDP-glucose 4-epimerase antibody
    see all

Anti-GALE antibody [1C4] 画像

  • All lanes : Anti-GALE antibody [1C4] (ab118033) at 1/500 dilution

    Lane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY control cDNA
    Lane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY GALE cDNA

    Lysates/proteins at 5 µg per lane.


    Predicted band size : 38 kDa
    HEK293T cell lysates were generated from transient transfection of the cDNA clone (RC201561)
  • All lanes : Anti-GALE antibody [1C4] (ab118033) at 1/500 dilution

    Lane 1 : HepG2 cell lysate
    Lane 2 : HeLa cell lysate
    Lane 3 : HT29 cell lysate
    Lane 4 : A549 cell lysate
    Lane 5 : COS7 cell lysate
    Lane 6 : Jurkat cell lysate
    Lane 7 : MDCK cell lysate
    Lane 8 : PC12 cell lysate
    Lane 9 : MCF7 cell lysate

    Lysates/proteins at 35 µg per lane.


    Predicted band size : 38 kDa
    HEK293T cell lysates were generated from transient transfection of the cDNA clone (RC201561)

Anti-GALE antibody [1C4] (ab118033) 使用論文

ab118033 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"