製品の概要

  • 製品名Anti-GADD45GIP1 antibody
    GADD45GIP1 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to GADD45GIP1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length protein, corresponding to amino acids 1-222 of Human GADD45GIP1 (NP_443082).

  • ポジティブ・コントロール
    • A431 lysate, transfected 293T cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab88769 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 25 kDa.

ターゲット情報

  • 機能Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity.
  • 組織特異性Widely expressed. Highly expressed in the thyroid gland, heart, lymph nodes, trachea and adrenal tissues. Expressed at lower level in liver skeletal muscle, kidney, pancreas, testis, ovary and stomach. Barely detectable in adrenal adenoma and papillary thyroid cancer.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
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Anti-GADD45GIP1 antibody 画像

  • Anti-GADD45GIP1 antibody (ab88769) at 1 µg + A431 cell lysate at 50 µg

    Predicted band size : 25 kDa
    Observed band size : 25 kDa
  • All lanes : Anti-GADD45GIP1 antibody (ab88769) at 1 µg/ml

    Lane 1 : transfected 293T lysate
    Lane 2 : non transfected 293T lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 25 kDa
    Observed band size : 23 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 27 kDa. We are unsure as to the identity of these extra bands.

Anti-GADD45GIP1 antibody (ab88769) 使用論文

ab88769 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"