製品の概要

  • 製品名Anti-GADD45GIP1 antibody
    GADD45GIP1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to GADD45GIP1
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    A synthesized peptide derived from an internal region of Human GADD45GIP1.

  • ポジティブ・コントロール
    • Human brain tissue

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab111254 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity.
  • 組織特異性Widely expressed. Highly expressed in the thyroid gland, heart, lymph nodes, trachea and adrenal tissues. Expressed at lower level in liver skeletal muscle, kidney, pancreas, testis, ovary and stomach. Barely detectable in adrenal adenoma and papillary thyroid cancer.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
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    • CR6-interacting factor 1 antibody
    • CRIF1 antibody
    • G45IP_HUMAN antibody
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    • Growth arrest and DNA damage inducible GADD45G interacting protein antibody
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    • PLINP 1 antibody
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    see all

Anti-GADD45GIP1 antibody 画像

  • Immunohistochemistry analysis of paraffin-embedded Human brain tissue, using 1/50 ab111254. The picture on the right is treated with the synthesized peptide

Anti-GADD45GIP1 antibody (ab111254) 使用論文

ab111254 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab111254.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"