Anti-GAD65 抗体 - Neuronal Marker (ab2348)

製品の概要

  • 製品名Anti-GAD65 antibody - Neuronal Marker
    GAD65 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to GAD65 - Neuronal Marker
  • 特異性This antibody reacts with a 65 kD protein, known as GAD (Glutamate Decarboxylase)
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Rat, Human
  • 免疫原

    Synthetic peptide (Human).

  • ポジティブ・コントロール
    • Pancreas
  • 特記事項


    Two forms of GAD exist in adults, GAD 65 and GAD 67, which are encoded by different genes. GAD 65 and GAD 67 are expressed in most GABA containing neurons. GAD 65 appears to be targeted to the membrane and nerve ending, where as GAD 67 is more widely distributed throughout the cell.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab2348 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/25 - 1/50. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

ターゲット情報

  • 機能Catalyzes the production of GABA.
  • 配列類似性Belongs to the group II decarboxylase family.
  • 翻訳後修飾Phosphorylated; which does not affect kinetic parameters or subcellular location.
    Palmitoylated; which is required for presynaptic clustering.
  • 細胞内局在Cytoplasm > cytosol. Cytoplasmic vesicle. Cell junction > synapse > presynaptic cell membrane. Golgi apparatus membrane. Associated to cytoplasmic vesicles. In neurons, cytosolic leaflet of Golgi membranes and presynaptic clusters.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 65 kDa glutamic acid decarboxylase antibody
    • DCE 2 antibody
    • DCE2 antibody
    • DCE2_HUMAN antibody
    • GAD 2 antibody
    • GAD 65 antibody
    • GAD-2 antibody
    • GAD-65 antibody
    • Gad2 antibody
    • Glutamate decarboxylase 2 (pancreas) antibody
    • Glutamate Decarboxylase 2 (pancreatic islets and brain 65kDa) antibody
    • Glutamate decarboxylase 2 antibody
    • Glutamate Decarboxylase 65 antibody
    • Glutamate decarboxylase 65 kDa isoform antibody
    • Glutamic Acid Decarboxylase 2 antibody
    • Glutamic Acid Decarboxylase 65 antibody
    • MGC161605 antibody
    • MGC161607 antibody
    see all

Anti-GAD65 antibody - Neuronal Marker 画像

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human pancreas tissue, staining GAD65 with ab2348.

Anti-GAD65 antibody - Neuronal Marker (ab2348) 使用論文

ab2348 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"