製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to GABRR1
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cat, Dog
  • 免疫原

    Synthetic peptide to a region within N terminal amino acids 36-85 (MSKKGRPQRQ RREVHEDAHK QVSPILRRSP DITKSPLTKS EQLLRIDDHD) of Human GABRR1 (NP_002033)

  • ポジティブ・コントロール
    • Hela cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab85667 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 56 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能
    GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-1 GABA receptor could play a role in retinal neurotransmission.
  • 組織特異性
    Highly expressed in the retina and in a lesser extent in brain, lung and thymus.
  • 配列類似性
    Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRR1 sub-subfamily.
  • 細胞内局在
    Cell junction > synapse > postsynaptic cell membrane. Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • bA135P14.1 (gamma-aminobutyric acid (GABA) receptor rho 1) antibody
    • GABA(A) receptor subunit rho-1 antibody
    • GABA(C) receptor antibody
    • GABRR1 antibody
    • gamma aminobutyric acid receptor rho 1 antibody
    • gamma-aminobutyric acid (GABA) A receptor rho-1 antibody
    • gamma-aminobutyric acid (GABA) receptor rho 1 antibody
    • Gamma-aminobutyric acid receptor subunit rho-1 antibody
    • GBRR1_HUMAN antibody
    • MGC163216 antibody
    see all

画像

  • Anti-GABRR1 antibody (ab85667) at 1 µg/ml (in 5% skim milk / PBS buffer) + Hela cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 56 kDa
    Observed band size : 56 kDa
    Additional bands at : >90 kDa. We are unsure as to the identity of these extra bands.

プロトコール

参考文献

ab85667 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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