製品の概要

  • 製品名Gabapentin
  • 製品の詳細
    α2δ Ligand
  • 生理活性の詳細Interacts with the α2δ subunit of L-type voltage gated Ca2+ channels. Disrupts calcium channel trafficking. Anticonvuslant and analgesic in vivo.

    Also available in simple stock solutions (ab146685) - add 1 ml of water to get an exact, ready-to-use concentration.
  • 精製度> 99%

製品の特性

    Gabapentin (ab120219) 使用論文

    This product has been referenced in:
    • Hendrich J  et al. Pharmacological disruption of calcium channel trafficking by the alpha2delta ligand gabapentin. Proc Natl Acad Sci U S A 105:3628-33 (2008). Read more (PubMed: 18299583) »
    • Taylor CP  et al. Pharmacology and mechanism of action of pregabalin: the calcium channel alpha2-delta (alpha2-delta) subunit as a target for antiepileptic drug discovery. Epilepsy Res 73:137-50 (2007). Read more (PubMed: 17126531) »
    • Sills GJ The mechanisms of action of gabapentin and pregabalin. Curr Opin Pharmacol 6:108-13 (2006). Read more (PubMed: 16376147) »

    See 1 Publication for this product

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