Gabapentin, alpha2delta Ligand (ab120219)
Key features and details
- α2δ Ligand
- CAS Number: 60142-96-3
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
Gabapentin, alpha2delta Ligand -
製品の詳細
α2δ Ligand -
生理活性の詳細
Interacts with the α2δ subunit of L-type voltage gated Ca2+ channels. Disrupts calcium channel trafficking. Anticonvuslant and analgesic in vivo.
Also available in simple stock solutions (ab146685) - add 1 ml of water to get an exact, ready-to-use concentration. -
CAS 番号
60142-96-3 -
構造式
製品の特性
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体系名
2-[1-(Aminomethyl)cyclohexyl]acetic acid -
分子量
171.24 -
分子式
C9H17NO2 -
PubChem 登録番号
3446 -
保存方法
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in water to 100 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
NCC1(CC(=O)O)CCCCC1 -
由来
Synthetic
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研究分野
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (1)
ab120219 は 1 報の論文で使用されています。
- Andresen L et al. Gabapentin attenuates hyperexcitability in the freeze-lesion model of developmental cortical malformation. Neurobiol Dis 71:305-16 (2014). PubMed: 25158291