Anti-GABA Transporter 1 / GAT 1 抗体 (ab72448)
Key features and details
- Rabbit polyclonal to GABA Transporter 1 / GAT 1
- Suitable for: WB
- Reacts with: Rat
- Isotype: IgG
製品の概要
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製品名
Anti-GABA Transporter 1 / GAT 1 antibody
GABA Transporter 1 / GAT 1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to GABA Transporter 1 / GAT 1 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Rat -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.50
Constituents: 0.01% BSA, 50% Glycerol, 0.87% Sodium chloride, 0.238% HEPES -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab72448の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/1000. Detects a band of approximately 67 kDa (predicted molecular weight: 67 kDa).
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特記事項 |
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WB
1/1000. Detects a band of approximately 67 kDa (predicted molecular weight: 67 kDa). |
ターゲット情報
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機能
Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals. -
配列類似性
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A1 subfamily. -
ドメイン
The PDZ domain-binding motif is involved in the interaction with MPP5. -
細胞内局在
Cell membrane. Membrane. Localized at the plasma membrane and in a subset of intracellular vesicles. Localized at the presynaptic terminals of interneurons. - Information by UniProt
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参照データベース
- Entrez Gene: 79212 Rat
- SwissProt: P23978 Rat
- Unigene: 10035 Rat
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別名
- GABATHG antibody
- GABATR antibody
- GABT 1 antibody
see all
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (5)
ab72448 は 5 報の論文で使用されています。
- Zhang D et al. Identification of sodium homeostasis genes in Camelus bactrianus by whole transcriptome sequencing. FEBS Open Bio 12:864-876 (2022). PubMed: 35147292
- Wilson CS et al. Late adolescence mortality in mice with brain-specific deletion of the volume-regulated anion channel subunit LRRC8A. FASEB J 35:e21869 (2021). PubMed: 34469026
- Vasilev DS et al. Transient Morphological Alterations in the Hippocampus After Pentylenetetrazole-Induced Seizures in Rats. Neurochem Res N/A:N/A (2018). PubMed: 29936569
- Chen L et al. Involvement of upregulation of miR-210 in a rat epilepsy model. Neuropsychiatr Dis Treat 12:1731-7 (2016). WB . PubMed: 27471387
- Moldavan M et al. Localization and expression of GABA transporters in the suprachiasmatic nucleus. Eur J Neurosci 42:3018-32 (2015). PubMed: 26390912