製品の概要

  • 製品名Anti-GABA antibody
    GABA 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to GABA
  • 特異性Using a conjugate GABA-Glutaraldehyde-Protein, antibody specificity was performed with an ELISA test by competition experiments with the following compounds :
    CompoundCross-reactivity ratio (a)
    GABA-G-BSA1
    beta-Alanine-G-BSA1/10000
    Glycine-G-BSA1/20000
    D-Aspartate-G-BSA1/100000
    D-Glutamate-G-PPL1/>10000
    (a): GABA-G-BSA concentration/unconjugated or conjugated aminoacid concentration at half displacement. G = Glutaraldehyde, BSA = bovine serum albumin.
  • アプリケーション適用あり: ELISA, IHC-Frmore details
  • 免疫原

    Chemical/ Small Molecule by a Glutaraldehyde linker.

  • 特記事項


    The antiserum was tested using the free floating PAP technique on rat hippocampus and cerebellum. The anti-conjugated GABA antibodies gave a good staining between 1/2000 - 1/5000 dilution in these areas.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Concentration information loading...
  • 精製度Ammonium Sulphate Precipitation
  • 一次抗体 備考The antiserum was tested using the free floating PAP technique on rat hippocampus and cerebellum. The anti-conjugated GABA antibodies gave a good staining between 1/2000 - 1/5000 dilution in these areas.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab6443 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA Use at an assay dependent concentration.
IHC-Fr Use at an assay dependent concentration.

ターゲット情報

  • 関連性Gamma-aminobutyric acid (GABA) is a major inhibitory neurotransmitter. GABA acts at inhibitory synapses in the brain and spinal cord. Inhibition is provoked by GABA binding resulting in hyperpolarization of the synaptic transmembrane potential of the affected neuron. GABA binding causes ion channels to open allowing either the flow of chloride or potassium ions into or out of the cell.
  • 細胞内局在Cell Membrane, Cytoplasmic, Plasma membrane and Secreted
  • 別名
    • 4 aminobutanoic acid antibody
    • GABA antibody
    • Gamma amino butyric acid antibody
    • Gamma aminobutyric acid antibody

プロトコール

Anti-GABA antibody (ab6443) 使用論文

ab6443 has not yet been referenced specifically in any publications.

Product Wall

Ab6443 doesn't recognize GABA free.

Yes, see step 1 in immunohisto and cytochemistry protocol (link to protocol is on top right corner of datasheet).

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"