Anti-GABA 抗体 (ab62669)
Key features and details
- Chicken polyclonal to GABA
- Suitable for: ICC
- Reacts with: Species independent
- Isotype: IgY
製品の概要
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製品名
Anti-GABA antibody
GABA 一次抗体 製品一覧 -
製品の詳細
Chicken polyclonal to GABA -
由来種
Chicken -
特異性
Fixed tissue cross-reactivity tested with known targets at recommended dilution. No measurable glutaraldehyde-fixed tissue cross-reactivity (<1:1000) against: L-alanine, D/L-aspartate, agmatine, D/L-arginine, L-citrulline, L-cysteine, D/L-glutamate, D/L-glutamine, glutathione, glycine, L-histidine, L-isoleucine, L-lysine, L-leucine, L-methionine, L-asparagine, L-ornithine, L-proline, L-serine, taurine, L-threonine, L-valine, L-tryptophan, L-tyrosine. No measurable reactivity against formaldehyde fixed proteins -
アプリケーション
適用あり: ICCmore details -
種交差性
交差種: Species independent -
免疫原
Full length native protein (purified) corresponding to Cow GABA (Glutaraldehyde). 4-aminobutyrate cross-linked to purifed fraction V bovine serum albumin with glutaraldehyde.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
Preservative: 0.05% Thimerosal (merthiolate)
Constituent: 0.268% PBS -
Concentration information loading...
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精製度
IgY fraction -
特記事項(精製)
IgYs were separated from other yolk proteins by serial PEG6000 extractions using a modification of the method of Polsonet al Immunological Investigations. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgY -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab62669の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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ICC |
特記事項 |
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Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
ターゲット情報
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関連性
Gamma-aminobutyric acid (GABA) is a major inhibitory neurotransmitter. GABA acts at inhibitory synapses in the brain and spinal cord. Inhibition is provoked by GABA binding resulting in hyperpolarization of the synaptic transmembrane potential of the affected neuron. GABA binding causes ion channels to open allowing either the flow of chloride or potassium ions into or out of the cell. -
細胞内局在
Cell Membrane, Cytoplasmic, Plasma membrane and Secreted -
別名
- 4 aminobutanoic acid antibody
- GABA antibody
- Gamma amino butyric acid antibody
- Gamma aminobutyric acid antibody
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab62669 は 2 報の論文で使用されています。
- Ausborn J et al. Organization of the core respiratory network: Insights from optogenetic and modeling studies. PLoS Comput Biol 14:e1006148 (2018). PubMed: 29698394
- Estakhr J et al. Differential Control of Dopaminergic Excitability and Locomotion by Cholinergic Inputs in Mouse Substantia Nigra. Curr Biol 27:1900-1914.e4 (2017). PubMed: 28648825